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| CAS No.: | 3131-03-1 |
|---|---|
| Name: | mikamycin B |
| Molecular Structure: | |
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| Formula: | C45H54 N8 O10 |
| Molecular Weight: | 866.971 |
| Synonyms: | OstreogrycinB (6CI,7CI); Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-;12H-Pyrido[2,1-f]pyrrolo[2,1-l][1,4,7,10,13,16]oxapentaazacyclononadecine,cyclic peptide deriv.; Antibiotic PA 114B; Antibiotic PA 114B1; Glycine,N-[(3-hydroxy-2-pyridinyl)carbonyl]-L-threonyl-D-2-aminobutanoyl-L-prolyl-4-(dimethylamino)-N-methyl-L-phenylalanyl-4-oxo-L-2-piperidinecarbonyl-L-2-phenyl-,r-lactone; Mikamycin B; MikamycinIA; NSC 92554; PA 114B; Pristinamycin P 1; Streptogramin B; Vernamycin Ba |
| Density: | 1.38g/cm3 |
| Melting Point: | 198° |
| Boiling Point: | 1202.1°Cat760mmHg |
| Flash Point: | 680.8°C |
| Safety: | Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 227.96000 |
| LogP: | 2.13220 |
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Chemistry
Chemistry informtion about Mikamycin B (3131-03-1) is:
Synonyms: mikamycin B ; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo(L-Thr*-D-Abu-L-Pro-N-methyl-4-(dimethylamino)-L-Phe-4-oxo-L-2-piperidinecarbonyl-L-phenyl Gly-) ; Ostreogrycin B;Pristinamycin IA;Streptogramin B
MW: 866.957860 g/mol
MF: C45H54N8O10
Density: 1.38 g/cm3
Flash Point: 680.8 °C
Boiling Point: 1202.1 °C at 760 mmHg
Enthalpy of Vaporization: 184.6 kJ/mol
Following is the molecular structure of Mikamycin B (3131-03-1) is:
Toxicity Data With Reference
| 1. | orl-mus LD50:200 mg/kg | 85FZAT Index of Antibiotics from Actinomycetes Umezawa, H., et al., eds.,Tokyo, Japan.: University of Tokyo Press,1967,750. | ||
| 2. | ipr-mus LD50:350 µg/kg | 85ERAY Antibiotics: Origin, Nature, and Properties. 1 (1978),367. | ||
| 3. | scu-mus LD50:200 mg/kg | 85FZAT Index of Antibiotics from Actinomycetes Umezawa, H., et al., eds.,Tokyo, Japan.: University of Tokyo Press,1967,750. |
Safety Profile
Poison by ingestion, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
RIDADR: 3172
HazardClass: 6.1(b)
PackingGroup: III
Specification
Mikamycin B (3131-03-1) is a specific streptogramin group B antibiotic produced by Streptomyces graminofaciens and other bacteria.