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35554-08-6

Basic Information
CAS No.: 35554-08-6
Name: 1H,10H-Pyrrolo[1,2-c]purine-10,10-diol,2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-, hydrochloride(1:2), (3aS,4R,10aS)-
Molecular Structure:
Molecular Structure of 35554-08-6 (1H,10H-Pyrrolo[1,2-c]purine-10,10-diol,2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-, hydrochloride(1:2), (3aS,4R,10aS)-)
Formula: C10H17 N7 O4 . 2 Cl H
Molecular Weight: 372.26
Synonyms: 1H,10H-Pyrrolo[1,2-c]purine-10,10-diol,2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-,dihydrochloride, (3aS,4R,10aS)- (9CI); 1H,10H-Pyrrolo[1,2-c]purine-10,10-diol,2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-, dihydrochloride,[3aS-(3aa,4a,10aR*)]-; Saxitoxin, dihydrochloride (7CI)
Safety: A very deadly poison by ingestion, intravenous, and intraperitoneal routes. Used as a neuromuscular blocking agent. When heated to decomposition it emits very toxic fumes of NOx and HCl.
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Chemistry

Product Name: Saxitoxin dihydrochloride
The MF of Saxitoxin dihydrochloride (CAS NO.35554-08-6) is C10H19Cl2N7O4.

                   
The MW of Saxitoxin dihydrochloride (CAS NO.35554-08-6) is 372.2.
Synonyms of Saxitoxin dihydrochloride (CAS NO.35554-08-6): Clam poison dihydrochloride ; Mussel poison dihydrochloride ; STX dihydrochloride
Flash Point: 318.7 °C
Boiling Point: 603.3 °C

Uses

  Saxitoxin dihydrochloride (CAS NO.35554-08-6) is used as chemical reagent, organic intermediates, fine chemicals, pharmaceutical research and development.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
domestic animals - goat/sheep LD parenteral > 126ng/kg (0.000126mg/kg) BEHAVIORAL: GENERAL ANESTHETIC United States Patent Document. Vol. #3892847,
frog LDLo intraperitoneal 75ug/kg (0.075mg/kg)   Toxicon. Vol. 5, Pg. 25, 1967.
mouse LD50 intraperitoneal 8ug/kg (0.008mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 607, 1960.
mouse LD50 intravenous 3400ng/kg (0.0034mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 607, 1960.
mouse LD50 oral 263ug/kg (0.263mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA Toxicology and Applied Pharmacology. Vol. 2, Pg. 607, 1960.
rabbit LDLo intravenous 3ug/kg (0.003mg/kg)   "Venomous and Poisonous Animals and Noxious Plants of the Pacific Region," Keegan, H.L., and W.V. Macfarlane, eds., New York, Pergamon Press Inc., 1963Vol. -, Pg. 75, 1963.
rat LD50 intravenous 85ug/kg (0.085mg/kg)   Archivos de la Facultad de Medicina de Madrid. Vol. 8, Pg. 151, 1965.

Safety Profile

A very deadly poison by ingestion, intravenous, and intraperitoneal routes. Used as a neuromuscular blocking agent. When heated to decomposition it emits very toxic fumes of NOx and HCl.Safety information of Saxitoxin dihydrochloride (CAS NO.35554-08-6):
RIDADR  3172
HazardClass  6.1(a)
PackingGroup  I