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| CAS No.: | 35834-26-5 |
|---|---|
| Name: | ROSAMICIN |
| Article Data: | 2 |
| Molecular Structure: | |
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| Formula: | C31H51 N O9 |
| Molecular Weight: | 581.747 |
| Synonyms: | 4,17-Dioxabicyclo[14.1.0]heptadecane,cirramycin A1 deriv.; 4'-Deoxycirramycin A1; Antibiotic 67-694; Antibiotic M4365A2; Antibiotic T 1124C; Juvenimicin A3; M 4365A2; NSC 175150; Rosamicin;Rosaramicin; Sch 14947 |
| Density: | 1.17g/cm3 |
| Melting Point: | 119-122° |
| Boiling Point: | 734.7°Cat760mmHg |
| Flash Point: | 398.1°C |
| Hazard Symbols: |
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| Risk Codes: | 20/21/22 |
| Safety: | Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. Used as an antibacterial agent. |
| PSA: | 135.13000 |
| LogP: | 2.67040 |
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Chemistry
MF: C31H51NO9
MW: 581.74
EINECS: 252-742-1
Density: 1.17 g/cm3
Storage temp: 2-8°C
Flash Point: 398.1 °C
Index of Refraction: 1.532
Enthalpy of Vaporization: 122.39 kJ/mol
Boiling Point: 734.7 °C at 760 mmHg
Vapour Pressure: 6.47E-25 mmHg at 25°C
Product Categories: Miscellaneous Natural Products
Solubility methanol of Rosamicin (35834-26-5): 10 mg/mL, clear, light yellow
Synonyms: 12,16-Tetramethyl-5,13-dioxo-9-((3,4,6-trideoxy-3-(dimethylamino)-beta-d-xylo ; 4,17-Dioxabicyclo(14.1.0)heptadec-14-ene-10-acetaldehyde,3-ethyl-7-hydroxy-2,8 ; 4’-Deoxy-cirramycina(sub1 ; 4’-deoxycirramycina(sub1) ; Antibiotic67-694 ; Antibioticm4365a2 ; -Hexopyranosyl)oxy)- ; M-4365a2
Following is the molecular structure of Rosamicin (35834-26-5):
Toxicity Data With Reference
| 1. | orl-mus LD50:1000 mg/kg | 85ESA3 Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals 9 (1976),1071. | ||
| 2. | ipr-mus LD50:350 mg/kg | 85ERAY Antibiotics: Origin, Nature, and Properties 1 (1978),62. | ||
| 3. | scu-mus LD50:625 mg/kg | 85ERAY Antibiotics: Origin, Nature, and Properties 1 (1978),62. |
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx. Used as an antibacterial agent.
Safety Information Rosamicin (35834-26-5):
Hazard Codes: Xn
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Risk Statements: 20/21/22
20/21/22: Harmful by inhalation, in contact with skin and if swallowed
Safety Statements: 26-36
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 36: Wear suitable protective clothing
WGK Germany: 3
RTECS: JG6800000
F10:Keep under argon.
Specification
Rosamicin (35834-26-5) is a new antibacterial substance chemically a lipid soluble basic macrolide similar to erythromycin but with a better activity against Gram-negative bacteria.