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CAS No.: | 37280-35-6 |
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Name: | capreomycin IA |
Molecular Structure: | |
Formula: | C25H44 N14 O8 |
Molecular Weight: | 668.83 |
Synonyms: | CapreomycinIA;Cyclo[3-[[(3S)-3,6-diamino-1-oxohexyl]amino]-L-alanyl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-amino-b-alanyl-L-seryl] (9CI);1,4,7,10,13-Pentaazacyclohexadecane, cyclic peptide deriv. |
Density: | 1.75g/cm3 |
Melting Point: | 246-248° (dec) |
Boiling Point: | °Cat760mmHg |
Flash Point: | °C |
Safety: | Poison by intravenous route. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx. |
PSA: | 375.92000 |
LogP: | -2.04080 |
1. | orl-mus LD50:10 g/kg | 85GDA2 CRC Handbook of Antibiotic Compounds. 4 (1)(1980),288. | ||
2. | scu-mus LD50:514 mg/kg | 85GDA2 CRC Handbook of Antibiotic Compounds. 4 (1)(1980),288. | ||
3. | ivn-mus LD50:250 mg/kg | 85GDA2 CRC Handbook of Antibiotic Compounds. 4 (1)(1980),288. |
CAPREOMYCIN IA (37280-35-6) has the toxicity.
1.mouse LD50 intravenous 250mg/kg (250mg/kg) "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 288, 1980.
2.mouse LD50 oral 10gm/kg (10000mg/kg) "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 288, 1980.
3.mouse LD50 subcutaneous 514mg/kg (514mg/kg) "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 288, 1980.