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CAS No.: | 37661-08-8 |
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Name: | BACAMPICILLIN HYDROCHLORIDE |
Article Data: | 3 |
Molecular Structure: | |
Formula: | C21H27 N3 O7 S . Cl H |
Molecular Weight: | 501.988 |
Synonyms: | 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-; 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-,1-[(ethoxycarbonyl)oxy]ethyl ester, monohydrochloride, (2S,5R,6R)- (9CI);Ambacamp; Ambaxin; Bacacil; Bacampicillin-hydrochloride; Bacampicine;Becampicillin hydrochloride; Penglobe; Spectrobid |
Melting Point: | 171-176° (dec) |
Boiling Point: | 695.4°C at 760 mmHg |
Flash Point: | 374.3°C |
Safety: | Poison by intraperitoneal and intravenous routes. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. |
PSA: | 162.56000 |
LogP: | 3.12690 |
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Chemistry informtion about Bacampicillin Hydrochloride(CAS NO.37661-08-8) is:
IUPAC Name: 1-ethoxycarbonyloxyethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrochloride
Synonyms: Ambacamp ; Ambaxin ; Bacacil ; Bapc ; Becampicillin ; O)-3,3-Dimethyl-7-Oxo-,1-((Ethoxycarbonyl)Oxy)Ethylester,Hydrochloride ; Penglobe ; Bacampicillin Hydrochloride
MF: C21H28ClN3O7S
MW: 501.98
EINECS: 253-580-4
Flash Point: 364.1 °C
Enthalpy of Vaporization: 99.57 kJ/mol
Boiling Point: 678.4 °C at 760 mmHg
Vapour Pressure: 2.92E-18 mmHg at 25°C
Following is the molecular structure of Bacampicillin Hydrochloride(CAS NO.37661-08-8) is:
Bacampicillin Hydrochloride(CAS NO.37661-08-8) is a semisynthetic penicillin that is effective against gram-negative and gram-positive bacteria and is used to treat infections of the intestinal, urinary, and respiratory tracts.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 176mg/kg (176mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Chemotherapy Vol. 27(Suppl, |
mouse | LD50 | intravenous | 184mg/kg (184mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Chemotherapy Vol. 27(Suppl, |
mouse | LD50 | oral | 8529mg/kg (8529mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Chemotherapy Vol. 27(Suppl, |
mouse | LD50 | subcutaneous | 9475mg/kg (9475mg/kg) | BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Chemotherapy Vol. 27(Suppl, |
rat | LD50 | intravenous | 176mg/kg (176mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Chemotherapy Vol. 27(Suppl, |
rat | LD50 | oral | 10gm/kg (10000mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981. | |
rat | LD50 | subcutaneous | 10gm/kg (10000mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 23, Pg. 1735, 1981. |
Poison by intraperitoneal and intravenous routes. Mildly toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.
Bacampicillin Hydrochloride(CAS NO.37661-08-8) is a semisynthetic penicillin with the same activity and uses as ampicillin, but better absorbed on oral administration.