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Basic Information
CAS No.: 406-90-6
Name: 2,2,2-Trifluoroethyl vinyl ether
Article Data: 8
Molecular Structure:
Molecular Structure of 406-90-6 (2,2,2-Trifluoroethyl vinyl ether)
Formula: C4H5 F3 O
Molecular Weight: 126.078
Synonyms: Ether,2,2,2-trifluoroethyl vinyl (6CI,8CI); 2,2,2-Trifluoroethyl vinyl ether;Fluoromar; Fluoroxene; Fluroxene; Trifluoroethyl vinyl ether
Density: 1.121g/cm3
Boiling Point: 43°Cat760mmHg
Flash Point: °C
Solubility: 4mg/L(temperature not stated)
Hazard Symbols:
Risk Codes: 11-41-10
Safety: Poison by inhalation. Moderately toxic by intraperitoneal route. An experimental teratogen. Human systemic effects by inhalation: jaundice and liver function tests impaired. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of F−. Used as an anesthetic. See also FLUORIDES and ETHERS.
PSA: 9.23000
LogP: 1.70880
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Chemistry

IUPAC Name: 2,2,2-Trifluoroethoxyethene
The MF of 2,2,2-Trifluoroethyl vinyl ether (CAS NO.406-90-6) is C4H5F3O.

                                 
The MW of 2,2,2-Trifluoroethyl vinyl ether (CAS NO.406-90-6) is 126.08.
Synonyms of 2,2,2-Trifluoroethyl vinyl ether (CAS NO.406-90-6): Ethene, (2,2,2-trifluoroethoxy)- ; 2-Trifluoroethoxyethene ; (2,2,2-Trifluoroethoxy)ethene
Index of Refraction: 1.323 
Apperance: Volatile Liquid
Density: 1.121 g/ml
Flash Point: -30 °C
Boiling Point: 43 °C
Merck: 14,4202
BRN: 1745876
EINECS: 206-977-1

Uses

   2,2,2-Trifluoroethyl vinyl ether (CAS NO.406-90-6) is used as an inhalation anesthetic.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TCLo inhalation 2pph/90M (20000ppm) LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"

LIVER: LIVER FUNCTION TESTS IMPAIRED		 Anesthesiology. Vol. 37, Pg. 462, 1972.
mouse LCLo inhalation 4pph/1H (40000ppm)   British Journal of Anesthesia. Vol. 48, Pg. 399, 1976.
rat LD50 intraperitoneal 5600mg/kg (5600mg/kg)   Toxicology and Applied Pharmacology. Vol. 71, Pg. 84, 1983.

Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Safety Profile

Poison by inhalation. Moderately toxic by intraperitoneal route. An experimental teratogen. Human systemic effects by inhalation: jaundice and liver function tests impaired. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of F−. Used as an anesthetic. See also FLUORIDES and ETHERS.Safety information of 2,2,2-Trifluoroethyl vinyl ether (CAS NO.406-90-6):
Hazard Codes  FlammableF,IrritantXi
Risk Statements 
11 Highly Flammable
41 Risk of serious damage to eyes
10 Flammable
Safety Statements 
16 Keep away from sources of ignition - No smoking
36 Wear suitable protective clothing
39 Wear eye/face protection
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
RIDADR  1993
RTECS  KO4250000
Hazard Note  Flammable
HazardClass  3
PackingGroup  II

Standards and Recommendations

NIOSH REL: (Waste Anesthetic Gases) CL 2 ppm/1H

Specification

 2,2,2-Trifluoroethyl vinyl ether is non-flammable but combustible. Can form explosive mixtures with air. Reacts with strong oxidizing agents.