CAS No.475207-59-1,Sorafenib tosylate Suppliers

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Basic Information

Molecular Structure:
CAS No.:	475207-59-1
Name:	Sorafenib tosylate

Formula:	C₂₁H₁₆ClF₃N₄O₃
Molecular Weight:	637.03
Synonyms:	Sorafenib tosylate [USAN];1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate);4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N2-methylpyridine-2-carboxamide mono (4-methylbenzenesulfonate);BAY 43-9006;Nexavar(R);UNII-5T62Q3B36J;2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate);
EINECS:	641-758-8
Density:	1.454 g/cm³
Boiling Point:	523.3 °C at 760 mmHg
Flash Point:	270.3 °C
Appearance:	White to off-white crystalline powder
Risk Codes:	36/37/38
Safety:	28-26
PSA:	155.10000
LogP:	8.40910

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Chemistry

Molecular structure of Nexavar (CAS NO.475207-59-1) is:

Product Name: Nexavar
CAS Registry Number: 475207-59-1
IUPAC Name: 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
Molecular Weight: 464.82495 [g/mol]
Molecular Formula: C₂₁H₁₆ClF₃N₄O₃
XLogP3-AA: 4.1
H-Bond Donor: 3
H-Bond Acceptor: 7
Surface Tension: 51.7 dyne/cm
Density: 1.454 g/cm³
Flash Point: 270.3 °C
Enthalpy of Vaporization: 79.7 kJ/mol
Boiling Point: 523.3 °C at 760 mmHg
Vapour Pressure: 4.76E-11 mmHg at 25°C

Uses

Nexavar (CAS NO.475207-59-1) is commonly used as a potent RAF kinase inhibitor. It is also used as antineoplastic drug.

Specification

Nexavar , its cas register number is 475207-59-1. It also can be called Sorafenib tosylate [USAN] ; 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)urea mono(4-methylbenzenesulfonate) ; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N2-methylpyridine-2-carboxamide mono (4-methylbenzenesulfonate) ; BAY 43-9006 ; BAY43-9006 ; Nexavar(R) ; Sorafenib tosylate ; UNII-5T62Q3B36J ; 2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-, mono(4-methylbenzenesulfonate) .