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CAS No.: | 50-54-4 |
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Name: | QUINIDINE SULFATE |
Molecular Structure: | |
Formula: | C40H48N4O4•H2O4S |
Molecular Weight: | 746.925 |
Synonyms: | Quinidine bisulfate;Quinidine, sulfate (2:1) (salt);Quinitex;Cinchonan-9-ol,6'-methoxy-,(9S)-,sulfate (2:1) (salt);Auriquin;Quinidex;Quinidine sulfate anhydrous;Cin-Quin;Vanquin;Quinidate;QUINIDINE;Kinichron;(S)-[(4S,5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Cinchonan-9-ol, 6-methoxy-, (9S)-, sulfate (2:1) (salt);Quinidine monosulfate;Quinidine sulfate (salt);Cin quin;Quinora;Chinidine sulfate;Quinicardine;Quinidine sulfate;SK-Quinidine sulfate;Systodin;(9S)-6′-METHOXYCINCHONAN-9-OL SULFATE (2:1) (SALT);QUINIDINE SULPHATE;CINCHONAN-9-OL, 6′-METHOXY-, (9S)-, SULFATE (2:1) (SALT) (9CI); |
EINECS: | 200-046-3 |
Density: | g/cm3 |
Melting Point: | 212°C |
Boiling Point: | 495.9°Cat760mmHg |
Flash Point: | 253.7°C |
Hazard Symbols: | Xn |
Risk Codes: | 22 |
Safety: | Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also QUINIDINE. |
PSA: | 174.16000 |
LogP: | 6.65020 |
MF: C40H50N4O8S
MW: 746.91
EINECS: 200-046-3
Product Categories: Organics
Melting Point Quinidinesulfate(2:1)(salt) (50-54-4):: 212°C
IUPAC Name: (S)-[(5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol ; sulfuric acid
Synonyms: Quinidinemono sulfate ; (9S)-6’-methoxycinchonan-9-olsulfate(2:1)(salt) ; 6’-Methoxy-cinchonan-9-o(9s)-cinchonan-9-osulfate(2:1)(salt) ; 6’-Methoxycinchonan-9-olsulfate ; Chinidinesulfate ; Quinidate ; Quinidinemonosulfate ; Quinidinesulfate(2:1)(salt)
Following is the molecular structure of Quinidinesulfate(2:1)(salt) (50-54-4):
1. | orl-man TDLo:240 mg/kg/2W-I:EYE | JTCTDW Journal of Toxicology, Clinical Toxicology. 20 (1983),367. | ||
2. | orl-wmn TDLo:272 mg/kg/17D-I:CVS | AIMDAP Archives of Internal Medicine. 145 (1985),2051. | ||
3. | orl-man TDLo:40 mg/kg/2W-I:CVS | AIMDAP Archives of Internal Medicine. 145 (1985),2051. | ||
4. | orl-hmn TDLo:9600 mg/kg/8W:CNS,PUL | JAMAAP JAMA, Journal of the American Medical Association. 238 (1977),884. | ||
5. | orl-wmn TDLo:409 g/kg/14Y:CNS | JAMAAP JAMA, Journal of the American Medical Association. 237 (1977),2093. | ||
6. | orl-man TDLo:88 mg/kg/10D-I:SYS | GASTAB Gastroenterology. 70 (1976),1136. | ||
7. | orl-wmn TDLo:32 mg/kg/2D:SKN | DICPBB Drug Intelligence and Clinical Pharmacy. 16 (1982),615. | ||
8. | mul-man LDLo:30 mg/kg/2D-I:CVS,PUL | AIMEAS Annals of Internal Medicine. 16 (1942),571. | ||
9. | orl-rat LD50:456 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 18 (1968),1127. | ||
10. | ipr-rat LDLo:140 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),156. | ||
Reported in EPA TSCA Inventory.
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Safety Information of Quinidinesulfate(2:1)(salt) (50-54-4):
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 22-45
22: Do not breathe dust
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: 1544