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53935-32-3

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Basic Information
CAS No.: 53935-32-3
Name: 5-oxoprolylhistidylprolinamide 2,3-dihydroxybutanedioate (1:1)
Molecular Structure:
Molecular Structure of 53935-32-3 (5-oxoprolylhistidylprolinamide 2,3-dihydroxybutanedioate (1:1))
Formula: C16H22N6O4•C4H6O4
Molecular Weight: 480.54
Synonyms: L-Prolinamide,5-oxo-L-prolyl-L-histidyl-,tartrate;TRH-T;Protirelin tartrate;L-Pyroglutamyl-L-histidyl-L-prolineamide-L-tartrate;
Boiling Point: 978.4°C at 760 mmHg
Flash Point: 545.5°C
Safety: Moderately toxic by intravenous and intramuscular routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
PSA: 273.31000
LogP: -1.72690
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    PROTIRELIN TARTRATE

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    PROTIRELIN TARTRATE

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Toxicity Data With Reference

1.   

orl-rat LD50:18 g/kg

    TAKHAA    Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. 36 (1977),22A.
2.   

ipr-rat LD50:2700 mg/kg

    TAKHAA    Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. 36 (1977),22A.
3.   

scu-rat LD50:6600 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),727.
4.   

ivn-rat TDLo:580 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),727.
5.   

ims-rat TDLo:2900 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),727.
6.   

orl-mus LD50:16 g/kg

    TAKHAA    Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. 36 (1977),22A.
7.   

scu-mus LD50:5400 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),727.
8.   

ivn-mus LD50:520 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),727.
9.   

ims-mus LD50:3300 mg/kg

    NI

Safety Profile

Moderately toxic by intravenous and intramuscular routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
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