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| CAS No.: | 551-36-0 |
|---|---|
| Name: | 2-(diethylamino)ethyl 4-amino-2-hydroxybenzoate hydrochloride (1:1) |
| Molecular Structure: | |
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| Formula: | C12H18N2O3•ClH |
| Molecular Weight: | 274.78 |
| Boiling Point: | 408.7°C at 760 mmHg |
| Flash Point: | 201°C |
| Safety: | Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also ESTERS. |
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Chemistry
IUPAC Name: 2-Diethylaminoethyl 4-amino-2-hydroxybenzoate hydrochloride
Synonyms: HCl salz des p-amino-salicylsaeure-diaethylaminoaethylester [German] ; Oxyprocain hydrochloride ; p-Aminosalicylic acid, 2-(diethylamino)ethyl ester hydrochloride ; p-Aminosalicylsaeurediaethylaminoaethylester-chlorhydrat [German] ; Salicylic acid, 4-amino-, 2-(diethylamino)ethyl ester, hydrochloride ; Salicylic acid, p-amino-, 2-(diethylamino)ethyl ester, hydrochloride
The Molecular Formula of p-Aminosalicylic acid, 2-(diethylamino)ethyl ester hydrochloride (CAS NO.551-36-0):C13H21ClN2O3
The Molecular Weight of p-Aminosalicylic acid, 2-(diethylamino)ethyl ester hydrochloride (CAS NO.551-36-0):288.770440g/mol
The Molecular Structure of p-Aminosalicylic acid, 2-(diethylamino)ethyl ester hydrochloride (CAS NO.551-36-0):
Flash Point: 201 °C
Enthalpy of Vaporization: 68.65 kJ/mol
Boiling Point: 408.7 °C at 760 mmHg
Vapour Pressure: 2.9E-07 mmHg at 25°C
Toxicity Data With Reference
| 1. | orl-rat LD50:130 mg/kg | ZENBAX Zeitschrift fuer Naturforschung, Ausgabe B, Chemie, Biochemie, Biophysik, Biologie und Verwandten Gebieten. 6B (1951),183. | ||
| 2. | ipr-rat LDLo:190 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 1 (1951),154. | ||
| 3. | ivn-rat LDLo:36 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 1 (1951),154. | ||
| 4. | orl-mus LD50:135 mg/kg | ZENBAX Zeitschrift fuer Naturforschung, Ausgabe B, Chemie, Biochemie, Biophysik, Biologie und Verwandten Gebieten. 6B (1951),183. | ||
| 5. | ipr-mus LD50:115 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 1 (1951),154. | ||
| 6. | scu-mus LD50:282 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 8 (1958),708. | ||
| 7. | ivn-mus LD50:37 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 104 (1952),40. |
Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also ESTERS.