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55843-86-2

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Basic Information
CAS No.: 55843-86-2
Name: Miroprofen
Article Data: 1
Molecular Structure:
Molecular Structure of 55843-86-2 (Miroprofen)
Formula: C16H14N2O2
Molecular Weight: 266.299
Synonyms: Miroprofen;Antopen;Miroprofeno;2-(4-imidazo[1,2-a]pyridin-2-ylphenyl)propanoic acid;Miroprofene;Y-9213;Miroprofenum;
Density: 1.24g/cm3
Boiling Point: °Cat760mmHg
Flash Point: °C
Safety: Poison by ingestion, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Used as an analgesic and anti-inflammatory agent. When heated to decomposition it emits toxic fumes of NOx.
PSA: 54.60000
LogP: 3.18940
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Chemistry

IUPAC Name: 2-(4-Imidazo[1,2-a]pyridin-2-ylphenyl)propanoic acid
Synonyms of 4-Imidazo(1,2-a)pyridin-2-yl-α-methyl-benzeneacetic acid (CAS NO.55843-86-2) : Benzeneacetic acid, 4-imidazo[1,2-a]pyridin-2-yl-alpha-methyl- ; 2-(4-(Imidazo(1,2-a)pyridin-2-yl)phenyl)propionic acid ; 2-(p-(2-Imidazo(1,2-a)pyridyl)phenyl)propionic acid ; 4-Imidazo[1,2-a]pyridin-2-yl-a-methylbenzeneacetic Acid ; Antopen
InChI:InChI=1/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
CAS NO:55843-86-2
Molecular Formula:C16H14N2O2                                                          
Molecular Weight :266.2946             
Molecular Structure :
EINECS: 204-102-8
Index of Refraction: 1.641   
Surface Tension: 48.8 dyne/cm 
Density: 1.24 g/cm3 

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 696mg/kg (696mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA		 Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
mouse LD50 oral 570mg/kg (570mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 2102, 1978.
mouse LD50 subcutaneous 687mg/kg (687mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA		 Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 intraperitoneal 365mg/kg (365mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA		 Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 oral 292mg/kg (292mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA		 Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.
rat LD50 subcutaneous 372mg/kg (372mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: APLASTIC ANEMIA		 Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 993, 1981.

Safety Profile

Poison by ingestion, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Used as an analgesic and anti-inflammatory agent. When 4-Imidazo(1,2-a)pyridin-2-yl-α-methyl-benzeneacetic acid (CAS NO.55843-86-2) is heated to decomposition, it emits toxic fumes of NOx.