CAS No.56-85-9,L-Glutamine Suppliers

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Basic Information

Molecular Structure:
CAS No.:	56-85-9
Name:	L-Glutamine
Article Data:	87

Formula:	C₅H₁₀N₂O₃
Molecular Weight:	146.146
Synonyms:	(S)-2,5-Diamino-5-oxopentanoic acid;Glutamine (VAN);L-Glutamid;Glutamine (USP);(2S)-2-amino-4-carbamoylbutanoic acid;(2S)-2-amino-4-carbamoyl-butanoic acid;L-2-Aminoglutaramic acid;Pentanoic acid, 2,5-diamino-5-oxo-, (S)-;Glutamine [USAN];(2S)-2-azaniumyl-4-carbamoyl-butanoate;Levoglutamina;Cebrogen;Levoglutamidum [INN-Latin];L-(+)-Glutamine;Glumin (amino acid);Levoglutamid;Miglu-P;Levoglutamide [DCF:INN];L-Glutamic acid .gamma.-amide;2-Aminoglutaramic acid;Levoglutamida [INN-Spanish];L-Glutamic acid gamma-amide;Levoglutamide;Glavamin;Glutamic acid 5-amide;(2S)-2,5-diamino-5-oxopentanoic acid;Glutamic acid amide;2,5-Diamino-5-oxopentanoic acid, (S)-;L(+)-Glutamine;L(+)-Glutamic acid-5-amide;H-Gln-OH;Glutamine (P347);Glutamine;L-Glutamine FCC5;L-Gln-OH;L-Glutamine;L-Glutamine FCC4;L-2-Aminoglutaramidic acid;2-Aminoglutaramic acid, L-;L-Glutamic acid 5-amide;2-amino-4-carbamoyl-butanoic acid;
EINECS:	200-292-1
Density:	1.321 g/cm³
Melting Point:	185 °C (dec.)(lit.)
Boiling Point:	445.6 °C at 760 mmHg
Flash Point:	223.3 °C
Solubility:	water: 25 mg/mL
Appearance:	White crystalline powder
Hazard Symbols:	Xi
Risk Codes:	36-36/37/38
Safety:	26-24/25-36/37/39-27
PSA:	106.41000
LogP:	0.06440

Synthetic route

: 71989-20-3
N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With sodium azide In N,N-dimethyl-formamide at 50℃; for 24h;	97%

: C42H33ClN4NiO4

A: 56-85-9
L-glutamine

: (R)-N-(2-benzoyl-4-chlorophenyl)-2-[3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepine-4-yl]acetamide

Conditions

Conditions	Yield
With hydrogenchloride; water In methanol at 30℃; for 2h;	A n/a B 95%
With hydrogenchloride In methanol; water at 30℃; for 2h;	A 0.05 g B 95%

: 4-carbamoyl-2-[(E,Z)-4,4,4-trifluoro-3-oxo-1-butenylamino]butanoic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 70℃; for 20h;	92%

: 4-carbamoyl-2-[(E,Z)-4,4,4-trichloro-3-oxo-1-butenylamino]butanoic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 70℃; for 20h;	85%

: 56-86-0
L-glutamic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With phosphoenolpyruvic acid; Imidazole-HCl buffer; ammonium chloride; adenosine 5'-diphosphate; magnesium chloride at 37℃; for 6h; pyruvate kinase, glutamine synthetase;	79%
With ammonia unter der Einwirkung von Enzym-Praeparaten aus verschiedenen tierischen Geweben;
With ammonia unter der Einwirkung von Streptococcus-Arten in Gegenwart von d-Glucose;

: (S)-3-(5'-oxo-9λ4-boraspiro[bicyclo[3.3.1]nonane-9,2'-[1,3,2]oxazaborolidin]-4'-yl)propanamide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; water at 20℃; for 5h;	79%

: C5H10N2O3*H3N*ClH

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane	59%

: 1820-73-1
glutamic acid γ-hydrazide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ethanol; nickel

: 55878-80-3
N-trityl-L-glutamic acid 5-methyl ester

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ammonia Erwaermen des Reaktionsprodukts mit wss.Essigsaeure;

: 42749-49-5
5-amino-2(S)-{[(4-methylphenyl)sulfonyl]amino}-5-oxopentanoic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid; phenol

Raw Materials

56-85-9

Downstream Products

50-35-1

149-87-1

107-12-0

1602-41-1

132388-65-9

17105-15-6

Total:383 Page 1 of 11 1 2 3 4 5 6 …11 Next>>

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Consensus Reports

L-Glutamine (CAS NO.77668-42-9) is reported in EPA TSCA Inventory.

Specification

L-Glutamine, with the IUPAC Name of (2S)-2,5-Diamino-5-oxopentanoic acid, is one kind of white crystalline powder. And its Classification Code are including Dietary supplement; Drug / Therapeutic Agent; Human Data; Mutation data. L-Glutamine(CAS NO.56-85-9) is the most abundant amino acid (building block of protein) in the body. The popular amino acid L-Glutamine is found in protein powders, beans, meats, fish, poultry, dairy products, and of course. It is used in the gut and immune system to maintain optimal performance. 60% of free-form amino acids floating in skeletal muscles is L-Glutamine.

Physical properties about L-Glutamine are: (1)ACD/LogP: -1.576; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -4.08; (4)ACD/LogD (pH 7.4): -4.08; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 5; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 5; (12)Index of Refraction: 1.524; (13)Molar Refractivity: 33.837 cm³; (14)Molar Volume: 110.546 cm³; (15)Polarizability: 13.414 10-24cm³; (16)Surface Tension: 64.588996887207 dyne/cm; (17)Density: 1.322 g/cm³; (18)Flash Point: 223.272 °C; (19)Enthalpy of Vaporization: 77.128 kJ/mol; (20)Boiling Point: 445.568 °C at 760 mmHg

Uses of L-Glutamine:
1). L-Glutamine (CAS NO.77668-42-9) has been studied extensively over the past 10–15 years and has been shown to be useful in treatment of serious illnesses, injury, trauma, burns, cancer and its treatment related side-effects as well as in wound healing for postoperative patients.
2). Glutamine is also marketed as a supplement used for muscle growth in weightlifting, bodybuilding, endurance, and other sports.
3). Glutamine has also been taken to enhance brain function as it fuels two of the brain's most important neurotransmitters.
4). It has also been used in the treatment of ADHD, anxiety，and depression.
5). It has also been used in recovery programs to break sugar craving cycles in alcoholics and assist diabetics in the management of sugar cravings.
6). It is also used as an anti-inflammatory in the treatment of autoimmune diseases and preserves Glutathione levels in the liver.

You can still convert the following datas into molecular structure:
(1)InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1;
(2)InChIKey=ZDXPYRJPNDTMRX-VKHMYHEASA-N;
(3)SmilesC([C@@H](C(=O)O)N)CC(N)=O

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	27mg/kg/1W-I (27mg/kg)	BEHAVIORAL: EUPHORIA	American Journal of Psychiatry. Vol. 141, Pg. 1302, 1984.
mouse	LD50	oral	21700mg/kg (21700mg/kg)		Drugs in Japan Vol. 6, Pg. 228, 1982.
rat	LD50	oral	7500mg/kg (7500mg/kg)		Drugs in Japan Vol. 6, Pg. 228, 1982.