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| CAS No.: | 631-27-6 |
|---|---|
| Name: | GLYCLOPYRAMIDE |
| Molecular Structure: | |
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| Formula: | C11H14ClN3O3S |
| Molecular Weight: | 303.769 |
| Synonyms: | Gliclopiramida [INN-Spanish];1,1-Tetramethylen-4-<4-chlor-benzolsulfonyl>-semicarbazid;glycopyramide;Deamelin S;Urea,1-((p-chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl);1-(p-Chlorphenylsulfonyl)-3-(pyrrolidin-1-yl)-harnstoff;CPBU 7;glyclopyramide;Glyclopyramidum [INN-Latin];1-(p-Chlorobenzenesulfonyl)-3-pyrrolidin-1-ylurea;1-(4-chloro-benzenesulfonyl)-3-pyrrolidin-1-yl-urea; |
| Density: | 1.49g/cm3 |
| Melting Point: | 200°C |
| Boiling Point: | 161.5°C (rough estimate) |
| Safety: | Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl−, NOx, and SOx. |
| PSA: | 90.38000 |
| LogP: | 2.95270 |
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Chemistry
IUPAC Name: 1-(4-Chlorophenyl)sulfonyl-3-pyrrolidin-1-ylurea
Molecular Formula: C11H14ClN3O3S
Molecular Weight: 303.79g/mol
Density: 1.49 g/cm3
Melting Point: 199–201°C
Properties: plates from EtOH (aq)
Freely Rotating Bonds: 2
Polar Surface Area: 69.31 Å2
Index of Refraction: 1.635
Molar Refractivity: 72.81 cm3
Molar Volume: 203.1 cm3
Polarizability: 28.86 ×10-24 cm3
Surface Tension: 66 dyne/cm
The Cas Register Number of Glycolpyramide is 631-27-6.The chemical synonyms of Glycolpyramide (CAS NO.631-27-6) are 4-Chloro-N-((1-pyrrolidinylamino)carbonyl)benzenesulfonamide ; 4-Chloro-N-(1-pyrrolidinylcarbamoyl)benzenesulfonamide ; 4-Chloro-N-(pyrrolidin-1-ylcarbamoyl)benzenesulfonamide ; Benzenesulfonamide, 4-chloro-N-[(1-pyrrolidinylamino)carbonyl]- ; 1-((p-Chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl)urea ; 1-(p-Chlorobenzenesulfonyl)-3-pyrrolidin-1-ylurea ; Benzenesulfonamide, 4-chloro-N-((1-pyrrolidinylamino)carbonyl)- (9CI) ; Deamelin-S ; Gliclopiramida [Spanish] ; Glyclopyramide ; Urea, 1-((p-chlorophenyl)sulfonyl)-3-(1-pyrrolidinyl)- .The molecular structure of Glycolpyramide (CAS NO.631-27-6) is
.
Uses
Glycolpyramide (CAS NO.631-27-6) is used as pharmaceutical.
Toxicity Data With Reference
| 1. | orl-rat LD50:4100 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 11 (1977),1605. | ||
| 2. | ipr-rat LD50:1620 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 11 (1977),1605. | ||
| 3. | orl-mus LD50:8910 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 11 (1977),1605. | ||
| 4. | ipr-mus LD50:1600 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 11 (1977),1605. | ||
| 5. | scu-mus LD50:5500 mg/kg | KSRNAM Kiso to Rinsho. Clinical Report. 11 (1977),1605. |
Safety Profile
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl−, NOx, and SOx.