Products Categories
| CAS No.: | 75757-64-1 |
|---|---|
| Name: | Shiga toxin |
| Molecular Structure: | |
|
|
|
| Formula: | N/A |
| Molecular Weight: | 0 |
| Synonyms: | Vero cell toxin;S. dysenteriae toxin;Shigella dysenteriae type I toxin;Toxin, shigella dysenteriae;Shigella toxin (Shigella dysenteriae); |
| Hazard Symbols: | A poison. |
| Risk Codes: | A poison.:; ">  A poison.:; |
| Safety: | A poison by parenteral, intraperitoneal, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors. |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 97730-31-9(S)-4'-(2-Methylbutyl)Biphenyl-4-Carbonitrile
- Total:2 Page 1 of 1 1
What can I do for you?
Get Best Price
Chemistry
Chemistry informtion about Shigella Dysenteriae Toxin (CAS NO.75757-64-1) is:
Synonyms: Shiga Toxin ; Toxin, Shigella Dysenteriae
MF: C54H99NO18
MW: 1050.3598
Density: 1.23 g/cm3
Flash Point: 641.3 °C
Boiling Point: 1136.7 °C at 760 mmHg
Enthalpy of Vaporization: 189.33 kJ/mol
Following is the molecular structure of Shigella Dysenteriae Toxin (CAS NO.75757-64-1) is:
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 250ng/kg (0.00025mg/kg) | peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) | Journal of Immunology. Vol. 130, Pg. 380, 1983. |
| mouse | LD50 | intravenous | 450ng/kg (0.00045mg/kg) | peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) | Journal of Immunology. Vol. 130, Pg. 380, 1983. |
| mouse | LDLo | parenteral | 2ug/kg (0.002mg/kg) | peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) behavioral: tremor behavioral: convulsions or effect on seizure threshold | Journal of Neuropathology and Experimental Neurology. Vol. 44, Pg. 496, 1985. |
| rabbit | LD50 | intravenous | 2200pg/kg (0.0000022mg/kg) | peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) | Journal of Immunology. Vol. 130, Pg. 380, 1983. |
| rabbit | LDLo | parenteral | 600ng/kg (0.0006mg/kg) | peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) gastrointestinal: nausea or vomiting | Journal of Neuropathology and Experimental Neurology. Vol. 44, Pg. 496, 1985. |
| rat | LDLo | parenteral | 1ug/kg (0.001mg/kg) | peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) gastrointestinal: nausea or vomiting | Journal of Neuropathology and Experimental Neurology. Vol. 44, Pg. 496, 1985. |
Safety Profile
A poison by parenteral, intraperitoneal, and intravenous routes. When heated to decomposition it emits acrid smoke and irritating vapors.
Analytical Methods
Shigella Dysenteriae Toxin (CAS NO.75757-64-1) act to inhibit protein synthesis within target cells by a mechanism similar to that of ricin toxin produced by Ricinus communis. After entering a cell, the protein functions as an N-glycosidase, cleaving several nucleobases from the RNA that comprises the ribosome, thereby halting protein synthesis.