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| CAS No.: | 7654-03-7 |
|---|---|
| Name: | Benmoxine |
| Article Data: | 14 |
| Molecular Structure: | |
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| Formula: | C15H16N2O |
| Molecular Weight: | 240.305 |
| Synonyms: | Nerusil;EINECS 231-619-6;Benmoxine;Benmoxin;Neuralex; |
| Density: | 1.109g/cm3 |
| Melting Point: | 93-94° |
| Boiling Point: | 353.6°C at 760 mmHg |
| Flash Point: | 127.6°C |
| Safety: | Poison by ingestion and intraperitoneal routes. An antidepressant. When heated to decomposition it emits toxic fumes of NOx. |
| PSA: | 44.62000 |
| LogP: | 3.64790 |
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- Total:2 Page 1 of 1 1
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Chemistry
Chemistry informtion about Neuralex (CAS NO.7654-03-7) is:
IUPAC Name: N'-(1-Phenylethyl)Benzohydrazide
Synonyms: Benmoxine ; 1-Benzoyl-2-(α-methylbenzyl)hydrazine ; 75-20-C ; Benzoic acid 2-(α-methylbenzyl) hydrazide ; Nerusil ; Neuralex
MF: C15H16N2O
MW: 240.300340 g/mol
Density: 1.109 g/cm3
Flash Point: 127.6 °C
Boiling Point: 353.6 °C at 760 mmHg
Vapour Pressure: 3.55E-05 mmHg at 25°C
Enthalpy of Vaporization: 59.85 kJ/mol
Following is the molecular structure of Neuralex (CAS NO.7654-03-7) is:
Uses
Neuralex (CAS NO.7654-03-7) is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s, but is now no longer marketed.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intraperitoneal | 325mg/kg (325mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 376, 1972. | |
| guinea pig | LD50 | oral | 460mg/kg (460mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 376, 1972. | |
| mouse | LD50 | intraperitoneal | 130mg/kg (130mg/kg) | Produits & Problemes Pharmaceutiques. Vol. 21, Pg. 621, 1966. | |
| mouse | LD50 | oral | 250mg/kg (250mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 376, 1972. | |
| rat | LD50 | intraperitoneal | 475mg/kg (475mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 376, 1972. | |
| rat | LD50 | oral | 675mg/kg (675mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 376, 1972. |
Safety Profile
Poison by ingestion and intraperitoneal routes. An antidepressant. When heated to decomposition it emits toxic fumes of NOx.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III