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814-80-2

Basic Information
CAS No.: 814-80-2
Name: Calcium lactate
Article Data: 18
Molecular Structure:
Molecular Structure of 814-80-2 (Calcium lactate)
Formula: C6H10CaO6
Molecular Weight: 218.22
Synonyms: Lacticacid, calcium salt (2:1) (8CI);Calcium DL-lactate;Propanoicacid, 2-hydroxy-, calcium salt (2:1);Calphosan;Conclyte Ca;E 327;L-Cal;Pationic 1230;Pationic 1240;Prequist Powder;Puracal PP/FCC;Puracal PP/USP;Tokal;Calcium Lactate FCC/USP;
EINECS: 212-406-7
Boiling Point: 227.6 °C at 760 mmHg
Flash Point: 109.9 °C
Appearance: White powder.
Risk Codes: 36/37/38
Safety: 26-36/37/39
PSA: 120.72000
LogP: -3.76580
Synthetic route

calcium oxide

57-50-1

Sucrose

814-80-2

calcium lactate

Conditions
ConditionsYield
In not given heating 3 h 25% saccharose soln. with CaO in excess at 197°C;;65%
In not given

calcium hydroxide

calcium oxide

57-50-1

Sucrose

814-80-2

calcium lactate

Conditions
ConditionsYield
In not given at 215°C and 30 at;; addn. of CaO in autoclave and saturation in heat at pH = 8.2; treatment with active carbon; concg.;;45%
In not given at 215°C and 30 at;; addn. of CaO in autoclave and saturation in heat at pH = 8.2; treatment with active carbon; concg.;;45%
56-81-5

glycerol

814-80-2

calcium lactate

Conditions
ConditionsYield
With water; C25H37IrN6(2+)*2F6P(1-); calcium hydroxide at 180℃; for 20h; Catalytic behavior; Reagent/catalyst; Autoclave;18%
849585-22-4

LACTIC ACID

calcium carbonate

814-80-2

calcium lactate

10326-41-7

D-Lactic acid

814-80-2

calcium lactate

Conditions
ConditionsYield
With calcium hydroxide In water
74-90-8

hydrogen cyanide

7664-93-9

sulfuric acid

75-07-0

acetaldehyde

calcium hydroxide

A

7664-41-7

ammonia

B

814-80-2

calcium lactate

Conditions
ConditionsYield
In sodium hydroxide reaction of 98% acetaldehyde in NaOH with HCN; heating soln with 50% H2SO4 and excess of Ca(OH)2; filtration in heat; cooling down;;
2280-44-6

D-Glucose

calcium oxide

814-80-2

calcium lactate

Conditions
ConditionsYield
In not given heating equimolar mixture at 70°C; reaction takes place in autoclave;; ultrapure;;
In not given heating equimolar mixture at 70°C; reaction takes place in autoclave;; ultrapure;;
2280-44-6

D-Glucose

calcium carbonate

814-80-2

calcium lactate

Conditions
ConditionsYield
In not given fermenting 13% glucose soln. in presence of CaCO3;;
In not given fermenting 13% glucose soln. in presence of CaCO3;;
849585-22-4

LACTIC ACID

814-80-2

calcium lactate

Conditions
ConditionsYield
With water; calcium oxide In glycerol Product distribution / selectivity;
With calcium carbonate In ethanol; water for 0.166667h; Sonication;
56-81-5

glycerol

calcium oxide

814-80-2

calcium lactate

Conditions
ConditionsYield
With copper(II) oxide In water at 230℃; for 0.5h; Sealed tube; Inert atmosphere; Green chemistry;
Raw Materials
10326-41-7
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Chemistry

Structure of Calcium lactate (CAS NO.814-80-2):

IUPAC Name: calcium 2-hydroxypropanoate 
Empirical Formula: C6H10CaO6
Molecular Weight: 218.218 
EINECS: 212-406-7 
Flash Point: 109.9 °C
Enthalpy of Vaporization: 53.96 kJ/mol
Boiling Point: 227.6 °C at 760 mmHg
Vapour Pressure: 0.015 mmHg at 25°C 
Product Categories: Nutritional fortification substances 
Synonyms of Calcium lactate (CAS NO.814-80-2): 2-Hydroxypropanoic acid calcium salt ; Calcium 2-hydroxypropanoate (1:2) ; Calphosan ; Conclyte calcium ; Hemicalcium L-lactate ; Lactic acid, calcium salt (2:1) ; Propanoic acid, 2-hydroxy-, calcium salt (2:1)

Uses

 Calcium lactate (CAS NO.814-80-2) is used in foods (as a baking powder) and given medicinally. the E number is E327.
1.When Calcium lactate (CAS NO.814-80-2) is added to chewing gum containing xylitol, it will increases the remineralization of tooth enamel.
 Calcium lactate (CAS NO.814-80-2) is also added to fresh-cut fruits  to keep them firm and extend their shelf life, such as cantaloupes.
2.In medicine, Calcium lactate (CAS NO.814-80-2) is most commonly used as an antacid,also used  to treat Calcium deficiencies. Calcium lactate (CAS NO.814-80-2) can be absorbed at various PHs ,so it  does not need to be taken with food for absorption.

Production

 Calcium lactate (CAS NO.814-80-2) is manufactured by the reaction of calcium carbonate (CaCO3) or hydroxide [Ca(OH)2] with lactic acid.
    Ca(OH)2 + HOCH2CH2CO2H → Ca(OCOCH2CH2OH)2

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 80mg/kg (80mg/kg)   International Journal of Toxicology. Vol. 17(Suppl,
mouse LDLo intravenous 140mg/kg (140mg/kg)   Journal of the American Pharmaceutical Association. Vol. 27, Pg. 484, 1938.
rabbit LDLo intravenous 180mg/kg (180mg/kg)   International Journal of Toxicology. Vol. 17(Suppl,

Safety Profile

Risk Statements: 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
TSCA Yes