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CAS No.: | 87051-43-2 |
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Name: | RITANSERIN |
Molecular Structure: | |
Formula: | C27H25 F2 N3 O S |
Molecular Weight: | 477.578 |
Synonyms: | Ritanserin;Tiserton |
Density: | 1.3g/cm3 |
Melting Point: | 145.5° |
Boiling Point: | 618.7°C at 760 mmHg |
Flash Point: | 328°C |
Hazard Symbols: | |
Risk Codes: | R36/37/38 |
Safety: | A poison by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx, F−, and SOx. |
PSA: | 65.85000 |
LogP: | 5.42090 |
IUPAC Name: 6-[2-[4-[bis(4-Fluorophenyl)methylene]-1-piperidyl]ethyl]-7-methyl-thiazolo[2,3-b]pyrimidin-5-one
Synonyms: 5H-Thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl- ; 6-(2-{4-[bis(4-Fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one ; (Ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one ; 4-[2-[4-[bis(4-Fluorophenyl)methylidene]-1-piperidyl]ethyl]-3-methyl-9-thia-2,6-diazabicyclo[4.3.0]nona-1,3,7-trien-5-one
Product Categories: API;Serotonin receptor
Molecular Structure of Ritanserin (CAS NO.87051-43-2) :
Molecular Formula of Ritanserin (CAS NO.87051-43-2) : C27H25F2N3OS
Molecular Weight of Ritanserin (CAS NO.87051-43-2) : 477.57
CAS NO: 87051-43-2
Index of Refraction: 1.646
Surface Tension: 46.4 dyne/cm
Density: 1.3 g/cm3
Flash Point: 328 °C
Enthalpy of Vaporization: 91.72 kJ/mol
Boiling Point: 618.7 °C at 760 mmHg
Vapour Pressure: 3.11E-15 mmHg at 25°C
Solubility : methanol: >10 mg/mL
Appearance: white solid
1.Ritanserin is a serotonin antagonist with wide-reaching possibilities for the treatment of many neurological disorders.
2.When used together with typical antipsychotics in the treatment of schizophrenia is able to decrease negative symptoms and adds some "atypicality" as parkinsonism is slightly decreased.
3.Possible effects on platelets have also been proposed.
1. | ipr-rat TDLo:5 mg/kg | BIPBU* Biological & pharmaceutical bulletin. 24 (2001),1431. |
A poison by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx, F−, and SOx.
Hazard Codes Xi
Risk Statements 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 22-26-36
S22:Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany 3