1000590-01-1

Basic information

• Product Name: C₁₅H₁₆BrNO
• Synonyms: C₁₅H₁₆BrNO
• CAS NO: 1000590-01-1
• Molecular Weight: 306.202
• Mol File: 1000590-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₆BrNO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₆BrNO(1000590-01-1)
• EPA Substance Registry System: C₁₅H₁₆BrNO(1000590-01-1)

Safety Data

• Hazardous Substances Data: 1000590-01-1(Hazardous Substances Data)

Upstream product

• 41458-65-5 6-amino-2,4-xylenol 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 1000590-07-7 C₁₈H₁₈BrNO₂ 

Relevant articles and documents

Microwave-assisted, palladium-catalyzed intramolecular direct arylation for the synthesis of novel fused heterocycles

An efficient synthesis of novel fused heterocycles has been established via microwave-assisted palladium-catalyzed intramolecular direct arylation. The acyclic aryl bromides are readily available from microwave-assisted one-pot annulation of N-(2-bromobenzyl)-2-aminophenols and ethyl 2-bromoalkanoates. The intramolecular direct arylation is then performed in the presence of palladium(II) acetate and dppf (10 mol% each) in toluene using potassium carbonate (2 equiv) as the base under microwave heating (150°C, 1 h) to afford the products in 43-99% yields. Steric effect is observed for Ar-Ar bond formation, giving a substantial amount of the debromination byproduct. Georg Thieme Verlag Stuttgart.