10009-44-6

Basic information

• Product Name: Propanoic acid, 2-(4-iodophenoxy)-, (R)-
• CAS NO: 10009-44-6
• Molecular Formula: C9H9IO3
• Molecular Weight: 292.073
• Mol File: 10009-44-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-(4-iodophenoxy)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-(4-iodophenoxy)-, (R)-(10009-44-6)
• EPA Substance Registry System: Propanoic acid, 2-(4-iodophenoxy)-, (R)-(10009-44-6)

Safety Data

• Hazardous Substances Data: 10009-44-6(Hazardous Substances Data)

Upstream product

• 540-38-5 p-Iodophenol 
• 32644-15-8 (S)-2-bromopropanoic acid 
• 402475-75-6 ethyl (+/-)-2-(4-iodophenoxy)propanoate 
• 10442-48-5 (+/-)-2-(4-iodophenoxy)propanoic acid 

Downstream Products

• 94050-90-5 (R)-2-(4-hydroxyphenoxy)propionic acid 

Relevant articles and documents

Preparation method of (R)-(+)-2-(4-hydroxyphenoxy) propionic acid

The invention provides a preparation method of (R)-(+)-2-(4-hydroxyphenoxy) propionic acid, and belongs to the technical field of pesticide intermediates. Phenol compounds (parachlorophenol, p-bromophenol, p-iodophenol or p-hydroxybenzenesulfonic acid) are adopted as raw materials and react with (S)-(-)-2-chloropropionic acid to synthesize R-(+)-2-(4-chlorophenoxy) propionic acid, and the (R)-(+)-2-(4-hydroxyphenoxy) propionic acid is obtained after hydrogen hydrolysis. The raw material phenol compound used in the invention is low in price and simple in process operation; and the method avoids using hydroquinone as a raw material, and solves the problems of high raw material cost, difficult product purification and low product quality caused by hydroquinone disubstituted impurities generated in the reaction when hydroquinone is used as a raw material for synthesis in the traditional method.

Microbial deracemization of alpha-substituted carboxylic acids.

An enzyme system of Nocardia diaphanozonaria JCM 3208 catalyzes the inversion of the chirality of various alpha-substituted carboxylic acids, such as 2-phenylpropanoic acid and 2-phenoxypropanoic acid derivatives, via a novel deracemization reaction.