1001026-35-2

Basic information

• Product Name: methyl 3-{[4-[[(tert-butyldimethylsilyl)oxy]methyl]benzyl]sulfonyl}propanoate
• Synonyms: methyl 3-{[4-[[(tert-butyldimethylsilyl)oxy]methyl]benzyl]sulfonyl}propanoate
• CAS NO: 1001026-35-2
• Molecular Weight: 386.585
• Mol File: 1001026-35-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-{[4-[[(tert-butyldimethylsilyl)oxy]methyl]benzyl]sulfonyl}propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-{[4-[[(tert-butyldimethylsilyl)oxy]methyl]benzyl]sulfonyl}propanoate(1001026-35-2)
• EPA Substance Registry System: methyl 3-{[4-[[(tert-butyldimethylsilyl)oxy]methyl]benzyl]sulfonyl}propanoate(1001026-35-2)

Safety Data

• Hazardous Substances Data: 1001026-35-2(Hazardous Substances Data)

Upstream product

• 874883-18-8 tert-butyl-[[4-(chloromethyl)phenyl]methoxy]dimethylsilane 
• 90030-48-1 sodium 3-methoxy-3-oxo-propane-1-sulfinate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 16473-35-1 4-(hydroxymethyl)benzyl chloride 

Downstream Products

• 1001026-37-4 {4-[[(tert-butyldimethylsilyl)oxy]methyl]phenyl}methanesulfonamide 
• 1451255-92-7 ethyl 5-cyano-6-(3-{[[4-(hydroxymethyl)benzyl]sulfonyl]carbamoyl}azetidin-1-yl)-2-methylnicotinate 
• 1471979-85-7 C₂₈H₃₈N₄O₆SSi 

Relevant articles and documents

Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. Separation of the antithrombotic effect and bleeding for candidate drug AZD1283

Synthesis and structure-activity relationships of ethyl 6-aminonicotinate acyl sulfonamides, which are potent antagonists of the P2Y12 receptor, are presented. Shifting from 5-chlorothienyl to benzyl sulfonamides significantly increased the pot