1001070-29-6 Usage
Structure
Pyrrolopyridine derivative with a fluorine atom at the 6 position and a phenylsulfonyl group attached at the 1 position
Potential pharmaceutical applications
Ability to interact with biological targets such as enzymes or receptors
Physicochemical properties
Presence of the fluorine atom and the sulfonyl group may impart specific properties that may be useful in drug development or medicinal chemistry research
Need for further studies
To fully understand the potential uses and properties of this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 1001070-29-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,0,7 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1001070-29:
(9*1)+(8*0)+(7*0)+(6*1)+(5*0)+(4*7)+(3*0)+(2*2)+(1*9)=56
56 % 10 = 6
So 1001070-29-6 is a valid CAS Registry Number.
1001070-29-6Relevant articles and documents
7-Azaindole derivatives as potential partial nicotinic agonists
Stoit, Axel R.,den Hartog, Arnold P.,Mons, Harry,van Schaik, Sjoerd,Barkhuijsen, Nynke,Stroomer, Cees,Coolen, Hein K.A.C.,Reinders, Jan Hendrik,Adolfs, Tiny J.P.,van der Neut, Martina,Keizer, Hiskias,Kruse, Chris G.
, p. 188 - 193 (2008/12/23)
We have investigated a series of 7-azaindoles as potential partial agonists of the α4β2 nicotinic acetylcholine receptor (nAChR). Three series of 7-azaindole derivatives have been synthesized and evaluated for rat brain neuronal nicotinic receptor affinity and functional activity. Compound (+)-51 exhibited the most potent nAChR binding (Ki = 10 nM). Compound 30A demonstrated both moderate binding affinity and partial agonist potency, thus representing a promising lead for the indications of cognition and smoking cessation.
