1001401-60-0

Basic information

• Product Name: 1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-, phenylMethyl ester, (5R)-
• Synonyms: 1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-, phenylMethyl ester, (5R)-;Suvorexant InterMediate;(5R)-1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-,phenylMethyl ester;(R)-Benzyl 5-methyl-1,4-diazepane-1-carboxylate/Suvorexant intermediate;New Intermediates;(5R)-Hexahydro-5-methyl-1H-1,4-diazepine-1-carboxylic acid phenylmethyl ester;Benzyl (5R)-5-methyl-1,4-diazepane-1-carboxylate;Benzyl(R)-5-methyl-1,4-diazepane-1-carboxylate
• CAS NO: 1001401-60-0
• Molecular Formula: C₁₄H₂₀N₂O₂
• Molecular Weight: 248.3208
• Mol File: 1001401-60-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-, phenylMethyl ester, (5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-, phenylMethyl ester, (5R)-(1001401-60-0)
• EPA Substance Registry System: 1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-, phenylMethyl ester, (5R)-(1001401-60-0)

Safety Data

• Hazardous Substances Data: 1001401-60-0(Hazardous Substances Data)

Usage

General Description

"1H-1,4-Diazepine-1-carboxylic acid, hexahydro-5-Methyl-, phenylMethyl ester, (5R)-" is a chemical compound that features in the family of diazepines. This organic compound consists of a seven-membered ring with two nitrogen atoms and a carboxylic acid group. The compound's structure also features a hexahydro-5-methyl group, which indicates that it includes a six-membered ring that is completely saturated (having no double or triple bonds) and has one methyl group. Lastly, it possesses a phenylMethyl ester group, suggesting the presence of an ester functional group connected to a phenyl group. The (5R)- in its name means that it is a specific enantiomer or spatial arrangement of the molecule. Overall, this compound is characterized by its complex carbon-nitrogen ring structure and various functional groups.

Upstream product

• 217972-87-7 benzyl 5-methyl-1,4-diazepane-1-carboxylate 
• 1030377-23-1 benzyl (2-((tert-butoxycarbonyl)amino)ethyl)(3-oxobutanoyl)carbamate 

Relevant articles and documents

NOVEL ROUTES OF SYNTHESIS FOR THE PREPARATION OF SUVOREXANT

The present invention relates to a process for the preparation of a compound of formula (A), Further, the present invention relates to the respective compound (A) as such and to its use in the preparation of antifungal agent.

SUBSTITUTED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to substituted diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.