1002557-66-5

Basic information

• Product Name: N-(biphenyl-2-ylmethyl)-N-{2-(tert-butylamino)-1-[1-(methylsulfonyl)-1H-pyrrol-2-yl]-2-oxoethyl}but-2-ynamide
• Synonyms: N-(biphenyl-2-ylmethyl)-N-{2-(tert-butylamino)-1-[1-(methylsulfonyl)-1H-pyrrol-2-yl]-2-oxoethyl}but-2-ynamide
• CAS NO: 1002557-66-5
• Molecular Weight: 505.638
• Mol File: 1002557-66-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(biphenyl-2-ylmethyl)-N-{2-(tert-butylamino)-1-[1-(methylsulfonyl)-1H-pyrrol-2-yl]-2-oxoethyl}but-2-ynamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(biphenyl-2-ylmethyl)-N-{2-(tert-butylamino)-1-[1-(methylsulfonyl)-1H-pyrrol-2-yl]-2-oxoethyl}but-2-ynamide(1002557-66-5)
• EPA Substance Registry System: N-(biphenyl-2-ylmethyl)-N-{2-(tert-butylamino)-1-[1-(methylsulfonyl)-1H-pyrrol-2-yl]-2-oxoethyl}but-2-ynamide(1002557-66-5)

Safety Data

• Hazardous Substances Data: 1002557-66-5(Hazardous Substances Data)

Upstream product

• 590-93-2 2-Butynoic acid 
• 119072-55-8 tert-butylisonitrile 
• 1924-77-2 2-phenylbenzylamine 
• 123892-38-6 1-(methylsulfonyl)-1H-pyrrole-2-carbaldehyde 

Relevant articles and documents

Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach

A series of isoindolinone compounds have been developed showing good in vitro potency on the Kv1.5 ion channel. By modification of two side chains on the isoindolinone scaffold, metabolically stable compounds with good in vivo PK profile could be obtained