100361-20-4

Basic information

• Product Name: Ethanone, 1-(2-phenyl-5-benzoxazolyl)-
• CAS NO: 100361-20-4
• Molecular Formula: C15H11NO2
• Molecular Weight: 237.258
• Mol File: 100361-20-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(2-phenyl-5-benzoxazolyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-phenyl-5-benzoxazolyl)-(100361-20-4)
• EPA Substance Registry System: Ethanone, 1-(2-phenyl-5-benzoxazolyl)-(100361-20-4)

Safety Data

• Hazardous Substances Data: 100361-20-4(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-phenyl-5-benzoxazolyl)- is a synthetic compound with the chemical formula C16H11NO2. It is a ketone derivative and belongs to the class of organic compounds known as benzoxazoles. This chemical is commonly used as a fluorescent whitening agent and optical brightener in various industrial and consumer products such as plastics, textiles, and paper. It works by absorbing ultraviolet light and reemitting it as visible light, thereby enhancing the perceived brightness and whiteness of the material it is added to. However, there are concerns about its potential ecological and health impacts, and it is important to handle and dispose of this chemical with care to minimize its adverse effects on the environment and human health.

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Relevant articles and documents

Cu-Catalyzed Synthesis of Benzoxazole with Phenol and Cyclic Oxime

A Cu-catalyzed straightforward synthesis of benzoxazoles from free phenols and cyclic oxime esters is reported. The mild reaction conditions tolerate various electron-withdrawing and electron-donating functional groups on both substrates, affording benzoxazoles in moderate to good yields. With this protocol, large-scale syntheses of Ezutromid and Flunoxaprofe in one or two steps are demonstrated. A catalytic mechanism, which includes Cu-catalyzed amination via inner-sphere electron transfer and consequent annulation, is proposed.

Method used for rapid preparation of benzo-heterocycle compound with physical grinding under solvent-free room temperature conditions

The invention discloses a method used for rapid preparation of benzo-heterocycle compound with physical grinding under solvent-free room temperature conditions. According to the method, glacial aceticacid is taken as a catalyst; at solvent-free room temperature conditions, physical grinding is adopted, reaction of 2-substituted arylamines (2-mercapto arylamine, 2-aminophenol, and o-phenylenediamine) and aromatic aldehydes is carried out using physical grinding. The method is friendly to the environment, is simple in operation, is safe, is low in cost, and is high in efficiency. Compared withthe prior art, the advantages are that: the method is suitable for a large amount of functional groups, yield is high, less by-product is generated, operation is simple, the method is safe, cost is low, and the method is friendly to the environment.

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

Using CuBr2 as an additive, the Pd-catalyzed intermolecular C-H-C-H cross-coupling between benzoxazoles and unactivated simple arenes has been developed. This protocol provides a straightforward approach for the biological activity of 2-arylbenzoxazole derivatives.