100367-39-3 Usage
Description
4-Bromo-2-methoxypyridine is an organic compound with the molecular formula C6H6BrNO. It is a derivative of pyridine, featuring a bromine atom at the 4th position, a methoxy group at the 2nd position, and a nitrogen atom in the ring structure. 4-Bromo-2-methoxypyridine is known for its reactivity and is commonly utilized in various chemical synthesis processes.
Uses
Used in Pharmaceutical Industry:
4-Bromo-2-methoxypyridine is used as a synthetic intermediate for the production of Imidazo[1,2-a]pyrimidines, which are a class of compounds with potential applications in the development of new drugs and pharmaceuticals. These compounds have been studied for their biological activities, including their potential as anti-cancer agents.
Used in Chemical Synthesis:
4-Bromo-2-methoxypyridine is used as a reactant in the Suzuki coupling reaction with 4-methoxyphenylboronic acid, resulting in the formation of 1,5-disubstituted pyridones. These pyridones are valuable building blocks in the synthesis of various organic compounds and have potential applications in the development of new materials and pharmaceuticals.
Used in Material Science:
4-Bromo-2-methoxypyridine serves as a starting material in the synthesis of crown-ester-bipyridines and viologens. These compounds are used in the development of novel materials with specific properties, such as ion-selective membranes and redox-active materials for energy storage applications.
Check Digit Verification of cas no
The CAS Registry Mumber 100367-39-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,6 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100367-39:
(8*1)+(7*0)+(6*0)+(5*3)+(4*6)+(3*7)+(2*3)+(1*9)=83
83 % 10 = 3
So 100367-39-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H6BrNO/c1-9-6-4-5(7)2-3-8-6/h2-4H,1H3
100367-39-3Relevant articles and documents
PYRROLIDINE GPR40 MODULATORS FOR THE TREATMENT OF DISEASES SUCH AS DIABETES
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Page/Page column 67, (2015/11/27)
The present invention provides compounds of Formula (I) or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, or a solvate thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.
2-ARYLBENZOTHIOPHENE DERIVATIVES OR PHARCEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF, AND PHARCEUTICAL COMPOSITION FOR THE DIAGNOSIS OR TREATMENT OF DEGENERATIVE BRAIN DISEASE CONTAINING THE SAME AS ACTIVE INGREDIENT
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Page/Page column 26, (2010/11/03)
2-arylbenzothiophene derivatives or pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition for the diagnosis or treatment of degenerative brain disease containing the same as an active ingredient. Since the 2-arylbenzothiophene derivatives of Formula 1 have a relatively high binding affinity for β-amyloid, they can be used as diagnostic reagents for diagnosing Alzheimer's disease at an early stage by non-invasive techniques when they are labeled with radioisotopes: wherein R1-R4, V, W, X, Y and Z are as defined in the Detailed Descript of the specification. Further, when the pharmaceutical composition containing the 2-arylbenzothiophene derivative binds with a low-molecular weight β-amyloid peptide binding compound, generation of malignant high-molecular weight β-amyloid deposits is minimized. Accordingly, the pharmaceutical composition can be used as a therapeutic agent of degenerative brain disease such as Alzheimer's disease.
Method of treating cancer
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, (2008/06/13)
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