100367-78-0

Basic information

• Product Name: 1-(2-bromo-5-nitrophenyl)hydrazine
• Synonyms: 1-(2-bromo-5-nitrophenyl)hydrazine;(2-bromo-5-nitrophenyl)hydrazine
• CAS NO: 100367-78-0
• Molecular Formula: C₆H₆BrN₃O₂
• Molecular Weight: 232.03474
• Mol File: 100367-78-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 331.1±32.0 °C(Predicted)
• Appearance: /
• Density: 1.869±0.06 g/cm3(Predicted)
• PKA: 3.75±0.10(Predicted)
• CAS DataBase Reference: 1-(2-bromo-5-nitrophenyl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-bromo-5-nitrophenyl)hydrazine(100367-78-0)
• EPA Substance Registry System: 1-(2-bromo-5-nitrophenyl)hydrazine(100367-78-0)

Safety Data

• Hazardous Substances Data: 100367-78-0(Hazardous Substances Data)

Usage

Description

1-(2-bromo-5-nitrophenyl)hydrazine is a chemical compound with the molecular formula C6H5BrN4O2. It is a hydrazine derivative featuring a bromo-nitrophenyl group attached to the hydrazine functional group. 1-(2-bromo-5-nitrophenyl)hydrazine is recognized for its unique structure and properties, making it a valuable building block in the synthesis of complex organic molecules. However, it is essential to handle this compound with care due to its potential hazards, which include causing irritation to the skin, eyes, and respiratory system if not properly managed.

Uses

Used in Pharmaceutical Synthesis:
1-(2-bromo-5-nitrophenyl)hydrazine is used as a reagent in the pharmaceutical industry for the preparation of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemical Production:
In the agrochemical industry, 1-(2-bromo-5-nitrophenyl)hydrazine is utilized as a reagent for the synthesis of different agrochemicals. Its role in creating these compounds aids in enhancing agricultural productivity and crop protection.
Used in Material Science:
1-(2-bromo-5-nitrophenyl)hydrazine is also employed in material science as a reagent for the development of new materials. Its incorporation into the synthesis process can lead to the creation of materials with improved properties, such as enhanced stability or specific functional characteristics.

Upstream product

• 10403-47-1 2-bromo 5-nitroaniline 

Downstream Products

• 847233-84-5 7-bromo-3-(4-chlorophenoxy)-2-methyl-4-nitro-1H-indole-1-acetic acid 1,1 dimethylethyl ester 
• 847233-86-7 3-(4-chlorophenoxy)-2-methyl-4-[(methylsulfonyl)amino]-1H-indole-1-acetic acid, 1,1-dimethylethyl ester 
• 847233-88-9 4-acetylamino-3-(4-chlorophenoxy)-2-methyl-1H-indole-1-acetic acid, 1,1-dimethylethyl ester 
• 847233-85-6 4-amino-3-(4-chlorophenoxy)-2-methyl-1H-indole-1-acetic acid, 1,1-dimethylethyl ester 
• 159547-14-5 2-(2-bromo-5-nitrophenyl)-5-n-butyl-2,4-dihydro-3H-1,2,4-triazol-3-one 

Relevant articles and documents

FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The invention is fused heterocyclic compounds of formula (I), and salts thereof, compositions thereof, and methods of use therefor. In particular, disclosed herein are certain fused heterocyclic compounds that can be useful for inhibiting protein kinase, including Bruton’ s tyrosine kinase (Btk), and for treating disorders mediated thereby.

FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The invention is fused heterocyclic compounds of formula (I), and salts thereof, compositions thereof, and methods of use therefor. In particular, disclosed herein are certain fused heterocyclic compounds that can be useful for inhibiting protein kinase, including Bruton's tyrosine kinase (Btk), and for treating disorders mediated thereby.

SUBSTITUTED INDOLE DERIVATIVES FOR PHARMACEUTICAL COMPOSITION FOR TREATING RESPIRATORY DISEASES

The present invention relates to substituted indoles of formula (I) useful as pharmaceutical compounds for treating respiratory disorders.