100372-26-7

Basic information

• Product Name: 3,3-dimethyl-6-phenylpiperidine-2,4-dione
• Synonyms: 3,3-dimethyl-6-phenylpiperidine-2,4-dione
• CAS NO: 100372-26-7
• Molecular Weight: 217.268
• Mol File: 100372-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,3-dimethyl-6-phenylpiperidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-dimethyl-6-phenylpiperidine-2,4-dione(100372-26-7)
• EPA Substance Registry System: 3,3-dimethyl-6-phenylpiperidine-2,4-dione(100372-26-7)

Safety Data

• Hazardous Substances Data: 100372-26-7(Hazardous Substances Data)

Upstream product

• 28123-28-6 2,4-dioxo-3,3-dimethyltetrahydropyridine 
• 118264-04-3 6-phenyl-5,6-dihydro-2,4(1H,3H)-pyridinedione 
• 74-88-4 methyl iodide 

Relevant articles and documents

Regioselective synthesis of substituted piperidine-2,4-diones and their derivatives via Dieckmann cyclisations

Abstract A flexible route to piperidine-2,4-diones variously substituted at the 6-, 5,6- and 2,6-positions, both with and without 1-substitution, is described; no N-protective group is required. A related regioselective Dieckmann cyclisation is also described that uses Davies' α-methylbenzylamine auxiliary and affords 6-substituted piperidine-2,4-diones enantioselectively.