10038-58-1Relevant articles and documents
α-Azido bisphosphonates: Synthesis and nucleotide analogues
Chamberlain, Brian T.,Upton, Thomas G.,Kashemirov, Boris A.,McKenna, Charles E.
experimental part, p. 5132 - 5136 (2011/08/09)
The first examples of α-azido bisphosphonates [(RO) 2P(O)]2CXN3 (1, R = i-Pr, X = Me; 2, R = i-Pr, X = H; 3, R = H, X = Me; 4, R = H, X = H) and corresponding β,γ- CXN3 dGTP (5-6) and α,β-CXN3 dATP (7-8) analogues are described. The individual diastereomers of 7 (7a/b) were obtained by HPLC separation of the dADP synthetic precursor (14a/b).
