1004-39-3 Usage
Description
4,6-Diamino-2-mercaptopyrimidine, also known as 2-thioadenosine derivatives, is a chemical compound with a brown-grey solid appearance. It is formed through the oxidation of 4,6-diamino-2-mercaptopyrimidine hydrate with hydrogen peroxide, resulting in a sulphinic acid. 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE has been found to possess various pharmacological activities, making it a promising candidate for different applications across various industries.
Uses
Used in Pharmaceutical Industry:
4,6-Diamino-2-mercaptopyrimidine is used as a pharmacological agent for its ability to inhibit platelet aggregation and induce coronary vasodilation. These properties make it a potential candidate for the development of drugs targeting cardiovascular diseases, where platelet aggregation and coronary vasodilation are critical factors in managing the condition.
Used in Research and Development:
In the field of research and development, 4,6-diamino-2-mercaptopyrimidine serves as a valuable compound for studying its various pharmacological activities and potential applications in drug discovery. Its unique chemical properties and interactions with other molecules make it an interesting subject for further investigation and experimentation.
Used in Chemical Synthesis:
Due to its chemical properties, 4,6-diamino-2-mercaptopyrimidine can be utilized as a building block or intermediate in the synthesis of other complex organic compounds. Its reactivity and functional groups make it a versatile component in the development of new molecules with specific applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1004-39-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1004-39:
(6*1)+(5*0)+(4*0)+(3*4)+(2*3)+(1*9)=33
33 % 10 = 3
So 1004-39-3 is a valid CAS Registry Number.
InChI:InChI=1S/C4H6N4S/c5-2-1-3(6)8-4(9)7-2/h1H,(H5,5,6,7,8,9)
1004-39-3Relevant articles and documents
Design, synthesis, and biological evaluation of 4-aminopyrimidine or 4,6-diaminopyrimidine derivatives as beta amyloid cleaving enzyme-1 inhibitors
Xu, Xiufeng,Peng,Wang, Junjie,Xu, Fengrong,Liang, Lei,Wang, Chao,Niu, Yan,Xu, Ping
, p. 926 - 933 (2019)
A series of novel aminopyrimidine and diaminopyrimidine derivatives were designed and optimized to improve their potency and permeability relative to lead compound 1 (IC50?=?37.4?μM), which was discovered in a previous virtual screening. The po
2-[(3,3,3-trifluoropropyl)thio]-6-amino-9H-purine and preparation method thereof
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Paragraph 0113-0114; 0119; 0122; 0123-0125; 0128, (2018/05/16)
The invention discloses 2-[(3,3,3-trifluoropropyl)thio]-6-amino-9H-purine and a preparation method thereof. 2-[(3,3,3-trifluoropropyl)thio]-6-amino-9H-purine can be used for preparation of 6-N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine
Method for synthesis of adenine (by machine translation)
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Paragraph 0034; 0086; 0106, (2017/02/24)
The invention discloses a synthetic method for adenine. Malononitrile and thiourea are employed as raw materials. The raw materials are subjected to a cyclization reaction under action of sodium alkoxide, and 4,6-diamino-2-sulfydryl pyrimidine. Then through three reaction routes, adenine is obtained. Though the method has many reaction steps, no refining or drying are needed for the product of each reaction step, the product can be used in the next reaction step, and the operation is simple. The raw materials are easily available, the prices are relatively low, the reaction conditions are mild, the operation is simple, the reaction steps are decreased, the reaction time is shortened, the overall reaction yield is high, and the synthetic method is suitable for industrial production.
