1004758-90-0

Basic information

• Product Name: 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole
• Synonyms: 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole
• CAS NO: 1004758-90-0
• Molecular Weight: 445.434
• Mol File: 1004758-90-0.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole(1004758-90-0)
• EPA Substance Registry System: 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole(1004758-90-0)

Safety Data

• Hazardous Substances Data: 1004758-90-0(Hazardous Substances Data)

Usage

Description

1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole is a complex organic compound characterized by a tetrazole ring fused to a biphenyl group and a trimethylsilylethoxymethyl group. The tetrazole ring, which contains four nitrogen atoms and one carbon atom, provides unique chemical properties to the molecule. The biphenyl group, consisting of two benzene rings connected by a single bond, is further functionalized by a bromomethyl group, enhancing its reactivity. The trimethylsilylethoxymethyl group serves as a protective functional group in organic synthesis. 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole may hold potential applications in various fields, including medicinal chemistry, materials science, and organic synthesis, due to its specific chemical features and reactivity.

Uses

Used in Medicinal Chemistry:
1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole is used as a building block for the development of new pharmaceuticals, leveraging its unique chemical properties and reactivity to create novel drug candidates with potential therapeutic applications.
Used in Materials Science:
In the field of materials science, 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole is used as a component in the synthesis of advanced materials, such as polymers and composites, that may exhibit specific properties like enhanced stability or reactivity.
Used in Organic Synthesis:
1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole is utilized as a synthetic intermediate for the preparation of various organic compounds. Its protective trimethylsilylethoxymethyl group allows for selective reactions and functional group manipulations, which are crucial in complex organic synthesis processes.
Different applications in different industries may include:
Used in Pharmaceutical Industry:
1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole is used as a key intermediate for the synthesis of targeted therapeutic agents, taking advantage of its unique structural features to design drugs with improved efficacy and selectivity.
Used in Chemical Research:
In the chemical research industry, 1-(2-trimethylsilylethoxymethyl)-5-(4'-bromomethylbiphenyl-2-yl)-1H-tetrazole is used as a model compound for studying reaction mechanisms and exploring new synthetic methodologies, contributing to the advancement of organic chemistry.

Downstream Products

• 1004759-14-1 (2S)-methyl 3-methyl-2-[pentanoyl-[[4-[2-(2-(2-trimethylsilylethoxymethyl)-2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate 
• 1004758-97-7 (2S)-methyl 3-methyl-2-[pentanoyl-[[4-[2-(1-(2-trimethylsilylethoxymethyl)-1H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate 
• 144689-63-4 olmesartan