1004972-21-7

Basic information

• Product Name: 2-amino-5-benzothiazol-2-ylpyrimidine
• Synonyms: 2-amino-5-benzothiazol-2-ylpyrimidine
• CAS NO: 1004972-21-7
• Molecular Weight: 228.277
• Mol File: 1004972-21-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-amino-5-benzothiazol-2-ylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-benzothiazol-2-ylpyrimidine(1004972-21-7)
• EPA Substance Registry System: 2-amino-5-benzothiazol-2-ylpyrimidine(1004972-21-7)

Safety Data

• Hazardous Substances Data: 1004972-21-7(Hazardous Substances Data)

Upstream product

• 2516-40-7 2-bromo-1,3-benzothiazole 
• 936250-22-5 (2-aminopyrimidin-5-yl)boronic acid 
• 1123-99-5 2-iodobenzothiazole 

Relevant articles and documents

New pyrimidylboronic acids and functionalized heteroarylpyrimidines by Suzuki cross-coupling reactions

We report the synthesis of 2-chloro-5-pyrimidylboronic acid (6) and 2-amino-5-pyrimidylboronic acid (8) by lithium-halogen exchange followed by reaction with triisopropylborate. Their reactivity with heteroaryl halides in Suzuki-Miyaura cross-coupling reactions has been evaluated. New highly functionalized 5-heteroarylpyrimidine derivatives 24-33 (heteroaryl = quinoline, pyridine, pyrimidine, pyrazine, thiophene, benzothiazole) have been obtained in synthetically useful yields. The X-ray structure of 6 reveals extensive intermolecular O-H...N hydrogen bonding in the crystal. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.