Cas 1005130-27-7,3-bromo-11,11-dimethyl-10-(2-methyl-2-propenyl)-9-azatricyclo[6.2.2.0~2,7~]dodeca-2,4,6-triene

1005130-27-7

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Basic information

Product Name: 3-bromo-11,11-dimethyl-10-(2-methyl-2-propenyl)-9-azatricyclo[6.2.2.0~2,7~]dodeca-2,4,6-triene
Synonyms: 3-bromo-11,11-dimethyl-10-(2-methyl-2-propenyl)-9-azatricyclo[6.2.2.0~2,7~]dodeca-2,4,6-triene
CAS NO:1005130-27-7
Molecular Formula: C17H22BrN
Molecular Weight: 320.26728
EINECS: N/A
Product Categories: N/A
Mol File: 1005130-27-7.mol
Article Data: 2

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-bromo-11,11-dimethyl-10-(2-methyl-2-propenyl)-9-azatricyclo[6.2.2.0~2,7~]dodeca-2,4,6-triene(CAS DataBase Reference)
NIST Chemistry Reference: 3-bromo-11,11-dimethyl-10-(2-methyl-2-propenyl)-9-azatricyclo[6.2.2.0~2,7~]dodeca-2,4,6-triene(1005130-27-7)
EPA Substance Registry System: 3-bromo-11,11-dimethyl-10-(2-methyl-2-propenyl)-9-azatricyclo[6.2.2.0~2,7~]dodeca-2,4,6-triene(1005130-27-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1005130-27-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1005130-27-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,5,1,3 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1005130-27:
(9*1)+(8*0)+(7*0)+(6*5)+(5*1)+(4*3)+(3*0)+(2*2)+(1*7)=67
67 % 10 = 7
So 1005130-27-7 is a valid CAS Registry Number.

1005130-27-7Upstream product

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1005130-27-7Relevant articles and documents

Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox 2) inhibitors

Cifuentes-Pagano, Eugenia,Saha, Jaideep,Csanyi, Gabor,Al Ghouleh, Imad,Sahoo, Sanghamitra,Rodriguez, Andres,Wipf, Peter,Pagano, Patrick J.,Skoda, Erin M.

, p. 1085 - 1092 (2013)

(1SR,4RS)-3,3-Dimethyl-1,2,3,4-tetrahydro-1,4-(epiminomethano)naphthalenes were synthesized in 2-3 steps from commercially available materials and assessed for specificity and effectiveness across a range of Nox isoforms. The N-pentyl and N-methylenethiophene substituted analogs 11g and 11h emerged as selective Nox2 inhibitors with cellular IC50 values of 20 and 32 μM, respectively.

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