100537-61-9

Basic information

• Product Name: 2-((4-nitrophenoxy)methyl)benzothiazole
• Synonyms: 2-((4-nitrophenoxy)methyl)benzothiazole
• CAS NO: 100537-61-9
• Molecular Weight: 286.311
• Mol File: 100537-61-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((4-nitrophenoxy)methyl)benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-nitrophenoxy)methyl)benzothiazole(100537-61-9)
• EPA Substance Registry System: 2-((4-nitrophenoxy)methyl)benzothiazole(100537-61-9)

Safety Data

• Hazardous Substances Data: 100537-61-9(Hazardous Substances Data)

Upstream product

• 106086-78-6 2-(bromomethyl)-1,3-benzothiazole 
• 100-02-7 4-nitro-phenol 
• 1798-11-4 4-nitrophenoxyacetic acid 
• 137-07-5 2-amino-benzenethiol 
• 37859-43-1 2-chloromethylbenzothiazole 

Downstream Products

• 197364-64-0 2-(4-aminophenoxymethyl)benzothiazole 

Relevant articles and documents

Synthesis, Biological Evaluation and Structure-Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors

A series of derivatives of the potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor diflapolin was designed, synthesized, and characterized by 1H NMR, 13C NMR, and elemental analysis. These novel compounds were biologically evaluated for their inhibitory activity against sEH and FLAP. Molecular modeling tools were applied to analyze structure-activity relationships (SAR) on both targets. Results show that even small modifications on the lead compound diflapolin markedly influence the inhibitory potential, especially on FLAP, suggesting very narrow SAR.