100548-82-1

Basic information

• Product Name: N-[4-(3-Butoxy-2-hydroxy-propoxy)-phenyl]-3-methylsulfanyl-propionamide
• Synonyms: N-[4-(3-Butoxy-2-hydroxy-propoxy)-phenyl]-3-methylsulfanyl-propionamide
• CAS NO: 100548-82-1
• Molecular Weight: 341.472
• Mol File: 100548-82-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[4-(3-Butoxy-2-hydroxy-propoxy)-phenyl]-3-methylsulfanyl-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-(3-Butoxy-2-hydroxy-propoxy)-phenyl]-3-methylsulfanyl-propionamide(100548-82-1)
• EPA Substance Registry System: N-[4-(3-Butoxy-2-hydroxy-propoxy)-phenyl]-3-methylsulfanyl-propionamide(100548-82-1)

Safety Data

• Hazardous Substances Data: 100548-82-1(Hazardous Substances Data)

Upstream product

• 7031-23-4 3-(methylthio)propionyl chloride 
• 94925-89-0 1-(4-Amino-phenoxy)-3-butoxy-propan-2-ol 
• 94925-74-3 1-Butoxy-3-(4-nitro-phenoxy)-propan-2-ol 
• 100-02-7 4-nitro-phenol 
• 125228-75-3 4-nitrophenyl 2-oxiranylmethyl ether 

Relevant articles and documents

Synthesis and antiallergic activity of dimethyl-2- (phenylcarbamoyl)ethylsulfonium p-toluenesulfonate derivatives

The derivatives of dimethyl-2-(phenylcarbamoyl)ethylsulfonium p- toluenesulfonates were synthesized and evaluated for antiallergic activity. The 2,3-dihydroxyethoxy group was introduced to the phenyl ring from the standpoint of lipophilicity and electronic effects of substituent. The IgE- induced rat passive cutaneous anaphylaxis (PCA) was inhibited by oral administration of several substituted 2-[(4- propoxyphenyl)carbamoyl]ethyldimethylsulfonium p-toluenesulfonate derivatives. Among them (±)-2-[N-[4-(3-ethoxy-2- hydroxypropoxy)phenyl]carbamoyl]ethyldimethylsulfonium p-toluenesulfonate (1a, IPD-1151T) was found to possess considerable activity in the PCA test, and it was launched as Suplatast tosilate in Japan.