1005499-19-3Relevant articles and documents
Synthesis of α-carboline
He, Linli,Allwein, Shawn P.,Dugan, Benjamin J.,Knouse, Kyle W.,Ott, Gregory R.,Zificsak, Craig A.
, p. 272 - 285 (2017/02/23)
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ALPHA-CARBOLINE DERIVATIVES AND METHODS FOR PREPARATION THEREOF
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Page/Page column 179-180, (2008/06/13)
To provide methods for preparing alpha-carboline derivatives in few steps, as well as conveniently and industrially advantageously. A method for preparation of a compound represented by Formula (II) or a salt thereof, comprising subjecting a compound represented by Formula (I) or a salt thereof to a ring closure reaction in the presence of a palladium catalyst, a ligand, and a base; a method for preparation of a compound represented by Formula (IX) or a salt thereof, comprising subjecting a compound represented by Formula (VII) or a salt thereof to a ring closure reaction in the presence of a palladium catalyst, a ligand, and a base, and subsequently to an aromatization reaction; and methods for preparation of compounds represented by Formulae (XV), (XVII), and (XIX) or a salt thereof, comprising subjecting respective compounds represented by Formulae (II) and (IX) or a salt thereof to a reaction for introducing a leaving group when necessary, and subsequently to a coupling reaction: wherein the symbols respectively represent the same meaning as defined in the present specification.
