1006061-57-9

Basic information

• Product Name: 1-(Azidomethyl)pyrene
• Synonyms: 1-(Azidomethyl)pyrene
• CAS NO: 1006061-57-9
• Molecular Formula: C₁₇H₁₁N₃
• Molecular Weight: 257.28934
• EINECS: -0
• Mol File: 1006061-57-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 66.0 to 70.0 °C
• Appearance: /
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Acetonitrile (Slightly, Sonicated), Chloroform (Slightly)
• CAS DataBase Reference: 1-(Azidomethyl)pyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Azidomethyl)pyrene(1006061-57-9)
• EPA Substance Registry System: 1-(Azidomethyl)pyrene(1006061-57-9)

Safety Data

• Hazardous Substances Data: 1006061-57-9(Hazardous Substances Data)

Usage

Description

1-(Azidomethyl)pyrene is a chemical compound characterized by its unique molecular structure, which features an azide group attached to a pyrene backbone. 1-(Azidomethyl)pyrene has garnered interest in various research and industrial applications due to its distinct properties and potential for further functionalization.

Uses

Used in Pharmaceutical Industry:
1-(Azidomethyl)pyrene is used as a chemical intermediate for the development of novel pharmaceuticals, particularly in the field of targeted cancer treatment. Its unique structure allows for the modulation of diiodo-BODIPY, a fluorescent dye with potential applications in cancer imaging and therapy. By incorporating 1-(Azidomethyl)pyrene into the molecular design, researchers can enhance the selectivity and efficiency of these compounds, ultimately improving their effectiveness in cancer treatment.
Used in Chemical Research:
1-(Azidomethyl)pyrene serves as a valuable research tool in the field of organic chemistry, where it can be employed for the synthesis of various complex molecules and materials. Its azide group provides a versatile handle for further functionalization, enabling the creation of new compounds with tailored properties and potential applications in areas such as drug discovery, materials science, and nanotechnology.

Upstream product

• 2595-90-6 1-bromomethylpyrene 
• 3029-19-4 pyrene-1-aldehyde 
• 24463-15-8 1-pyrenemethanol 

Downstream Products

• 1241412-92-9 C₄₉H₄₁N₅O₇ 
• 1309130-56-0 C₉₄H₈₆N₆O₄S₄ 
• 1309049-18-0 C₃₀H₂₇N₃O 
• 132183-40-5 2'-deoxy-5-O-(4,4'-dimethoxytrityl)-N⁶-(pyren-1-ylmethy)adenosine 
• 1334677-29-0 C₄₆H₃₄N₆O₅S 
• 1275611-01-2 (1R,3R,4R,7S)-1-(4,4'-dimethoxytrityloxymethyl)-7-hydroxy-3-[5-(1-(pyren-1-ylmethyl)-1H-1,2,3-triazol-4-yl)uracil-1-yl]-2,5-dioxabicyclo[2.2.1]heptane 

Relevant articles and documents

Polypeptide/Multiwalled carbon nanotube hybrid complexes stabilized through noncovalent bonding interactions

In this study, we used click chemistry to synthesize new linear polypeptide-g-pyrene polymers from a mono-azido-functionalized pyrene derivative (N3-Py) and several poly(γ-propargyl-l-glutamate) (PPLG) oligomers. Incorporating the pyrene units as side chains enhanced the α-helical conformations of these PPLG oligomers in the solid state, as determined using Fourier transform infrared (FTIR) spectroscopy; it also increased the temperature stability of the α-helical secondary structures of the grafted PPLG oligomers, relative to those of the pure PPLG species, as revealed through temperature-dependent FTIR spectroscopic analyses. In addition, the thermal properties of the PPLG-g-Py polypeptides (e.g., glass transition temperatures increased by ca. 100 °C) were superior to those of pure PPLG oligomers. Mixing the PPLG-g-Py oligomers with multiwalled carbon nanotubes (MWCNTs) in dimethylformamide led to the formation of highly dispersible PPLG-g-Py/MWCNT organic/inorganic hybrid complex materials. Fluorescence emission spectra revealed significant π-π stacking between the PPLG-g-Py oligomers and the MWCNTs in these complexes. 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014, 52, 321-329 Click chemistry is used to synthesize new linear polypeptide-g-pyrene polymers from a mono-azido-functionalized pyrene derivative (N3-Py) and several poly(γ-propargyl-l-glutamate) (PPLG) oligomers. Incorporating the pyrene units as side chains enhances the α-helical conformations of these PPLG oligomers in the solid state and increases the temperature stability of the α-helical secondary structures of the grafted PPLG oligomers, relative to those of the pure PPLG species. Copyright

Synthesis, photophysical and electrochemical properties and DSSC application of triphenylaminochalcone cored dendrimers with anthracene and pyrene as surface groups and triazolylcholanoate as the bridging unit

Triphenylaminochalcone-cored dendrimers decorated with anthracene and pyrene at the periphery have been synthesized by a convergent methodology using a click chemistry approach and characterized from spectral data and elemental analyses. All the dendrimers show excellent optical and electrochemical properties. Higher generation dendrimers exhibit better power conversion efficiency than lower-generation dendrimers when used as additives in dye-sensitized solar cells (DSSCs).

Building addressable libraries: A site-selective click-reaction strategy for rapidly assembling mass spectrometry cleavable linkers

A click-reaction was site-selectively carried out on 1000 and 12000 microelectrode arrays and characterized using TOF-SIMS.

Evaluation of readily accessible azoles as mimics of the aromatic ring of D-phenylalanine in the turn region of gramicidin S

The influence of replacing the d-phenylalanine residue with substituted and unsubstituted azoles on the structure and biological activity of the antibiotic gramicidinS was investigated against a representative panel of Gram-positive and Gram-negative bact