100632-81-3Relevant articles and documents
A Multicatalytic Approach to the Hydroaminomethylation of α-Olefins
Hanna, Steven,Holder, Jeffrey C.,Hartwig, John F.
supporting information, p. 3368 - 3372 (2019/02/24)
We report an approach to conducting the hydroaminomethylation of diverse α-olefins with a wide range of alkyl, aryl, and heteroarylamines at relatively low temperatures (70–80 °C) and pressures (1.0–3.4 bar) of synthesis gas. This approach is based on sim
Synthesis of biologically active amines via rhodium-bisphosphite-catalyzed hydroaminomethylation
Briggs, John R.,Klosin, Jerzy,Whiteker, Gregory T.
, p. 4795 - 4798 (2007/10/03)
(Chemical Equation Presented) We report the use of a highly regioselective rhodium-bisphosphite catalyst for olefin hydroaminomethylation. This catalyst system was successfully applied in the synthesis of two biologically active tertiary amines, ibutilide and aripiprazole.
Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides
-
, (2008/06/13)
The present invention provides novel sulfonanilide and benzene-alkylaminium compounds which are the products of processes utilizing novel intermediates. Both the novel compounds and the novel intermediates are useful for the therapeutic or prophylactic treatment of arrhythmic activity.