1006607-26-6

Basic information

• Product Name: C₂₆H₃₉N₅
• Synonyms: C₂₆H₃₉N₅
• CAS NO: 1006607-26-6
• Molecular Weight: 421.629
• Mol File: 1006607-26-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₉N₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₉N₅(1006607-26-6)
• EPA Substance Registry System: C₂₆H₃₉N₅(1006607-26-6)

Safety Data

• Hazardous Substances Data: 1006607-26-6(Hazardous Substances Data)

Upstream product

• 5142-23-4 3-methyladenine 
• 714956-88-4 (2E,6E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,6-dien-1-yl bromide 

Downstream Products

• 1006607-28-8 C₂₆H₄₁N₅ 

Relevant articles and documents

Synthesis, antimicrobial and antineoplastic activities for agelasine and agelasimine analogs with a β-cyclocitral derived substituent

Agelasines and agelasimines are antimicrobial and cytotoxic purine derivatives isolated from marine sponges (Agelas sp.). We have synthesized structurally simplified analogs of these natural products starting from β-cyclocitral. The novel compounds were found to be strong inhibitors of a wide variety of pathogenic microorganisms (incl. Mycobacterium tuberculosis) as well as cancer cell lines. The biological activities were generally in the same range as those previously found for the structurally more complex agelasines and agelasimines isolated in small amounts from natural sources. We also report for the first time that agelasine and agelasimine analogs inhibit growth of protozoa (Acanthamoeba castellanii and Acanthamoeba polyphaga). Acanthamoeba keratitis is an increasingly common and severe corneal infection, closely associated with contact lens wear.