100778-27-6

Basic information

• Product Name: 1,6-dibromo-1,6-dideoxy-2,5-di-O-p-tolylsulfonyl-D-mannitol
• Synonyms: 1,6-dibromo-1,6-dideoxy-2,5-di-O-p-tolylsulfonyl-D-mannitol
• CAS NO: 100778-27-6
• Molecular Weight: 616.346
• Mol File: 100778-27-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,6-dibromo-1,6-dideoxy-2,5-di-O-p-tolylsulfonyl-D-mannitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-dibromo-1,6-dideoxy-2,5-di-O-p-tolylsulfonyl-D-mannitol(100778-27-6)
• EPA Substance Registry System: 1,6-dibromo-1,6-dideoxy-2,5-di-O-p-tolylsulfonyl-D-mannitol(100778-27-6)

Safety Data

• Hazardous Substances Data: 100778-27-6(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 17107-32-3 1,6-dibromo-1,6-dideoxy-3,4-O-isopropylidene-D-mannitol 
• 100778-25-4 1,6-dibromo-1,6-dideoxy-3,4-O-isopropylidene-2,5-di-O-p-tolylsulfonyl-D-mannitol 

Relevant articles and documents

2,5:3,4-DIANHYDRO-1,6-DIDEOXY-6-(TRIMETHYLAMINO)-D-ALLITOL AND -D-GALACTITOL

A new, four-step synthesis of 2,5:3,6-dianhydro-1-deoxy-D-glucitol 16 was worked out, starting from 1,6-dibromo-1,6-dideoxy-D-mannitol.Compound 16 was converted into different 4-O-acyl derivatives, the 3,6-anhydro rings of which where opened with hydrogen bromide, yielding the corresponding 6-bromo compounds.These were converted, via the 6-azides, into the 6-(dimethylamino) derivatives, the sulfonic esters of which gave, on treatment with base, the 2,5:3,4-dianhydro-D-allitol and -D-galactitol derivatives.These were converted with methyl iodide into the corresponding quaternary salts.On biological testing, only the D-allitol derivative showed weak, muscarine-like activity.