1007884-60-7 Usage
Description
Methyl N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-5-[4-(4-2-[(2S)-pyrrolidin-2-yl]-1H-imidazol-5-ylphenyl)phenyl]-1H-imidazol-2-ylpyrrolidin-1-yl]butan-2-yl]carbamate is a complex organic compound with a unique molecular structure. It is characterized by the presence of various functional groups, including imidazole, pyrrolidine, and carbamate moieties. methyl N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-5-[4-(4-2-[(2S)-pyrrolidin-2-yl]-1H-imidazol-5-ylphenyl)phenyl]-1H-imidazol-2-ylpyrrolidin-1-yl]butan-2-yl]carbamate exhibits a high degree of stereoselectivity, with multiple chiral centers, which may contribute to its potential biological activity and applications.
Uses
Used in Pharmaceutical Industry:
Methyl N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-5-[4-(4-2-[(2S)-pyrrolidin-2-yl]-1H-imidazol-5-ylphenyl)phenyl]-1H-imidazol-2-ylpyrrolidin-1-yl]butan-2-yl]carbamate is used as a drug candidate for the treatment of hepatitis C (HCV). It is an impurity of Daclatasvir (D101500), a compound that inhibits the HCV protein NS5A, thereby exhibiting antiviral activity against the hepatitis C virus.
Used in Chemical Research:
Due to its complex structure and unique functional groups, methyl N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-5-[4-(4-2-[(2S)-pyrrolidin-2-yl]-1H-imidazol-5-ylphenyl)phenyl]-1H-imidazol-2-ylpyrrolidin-1-yl]butan-2-yl]carbamate can be used as a research tool in chemical and medicinal chemistry. It may serve as a starting material or intermediate in the synthesis of novel compounds with potential therapeutic applications.
Used in Drug Development:
methyl N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-5-[4-(4-2-[(2S)-pyrrolidin-2-yl]-1H-imidazol-5-ylphenyl)phenyl]-1H-imidazol-2-ylpyrrolidin-1-yl]butan-2-yl]carbamate's stereoselective nature and the presence of various functional groups make it a promising candidate for drug development. It can be further modified or used as a template to design new drugs targeting specific biological pathways or receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 1007884-60-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,7,8,8 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1007884-60:
(9*1)+(8*0)+(7*0)+(6*7)+(5*8)+(4*8)+(3*4)+(2*6)+(1*0)=147
147 % 10 = 7
So 1007884-60-7 is a valid CAS Registry Number.
1007884-60-7Relevant articles and documents
Monoglycosyl-containing heterocyclic compound for inhibiting hepatitis C viruses and preparation method
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, (2019/03/28)
The invention discloses a monoglycosyl-containing heterocyclic compound for inhibiting hepatitis C viruses and a preparation method. The monoglycosyl-containing heterocyclic compound has a chemical structure represented by a formula I shown in the description. The monoglycosyl-containing heterocyclic compound disclosed by the invention can be used for effectively inhibiting protease of the hepatitis C viruses and treating infection of the hepatitis C viruses (HCV).
Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors
Boucle, Sebastien,Tao, Sijia,Amblard, Franck,Stanton, Richard A.,Nettles, James H.,Li, Chengwei,McBrayer, Tamara R.,Whitaker, Tony,Coats, Steven J.,Schinazi, Raymond F.
, p. 3711 - 3715 (2015/08/11)
The design and synthesis of new non-symmetrical NS5A inhibitors with sulfur containing amino acids is reported along with their ability to block HCV replication in an HCV 1b replicon system. These compounds display EC50 values in the picomolar range with a large therapeutic index (>106). Moreover, cellular pharmacology studies show that our preferred compounds intracellularly deliver three potent NS5A inhibitors.
