100827-77-8 Usage
Description
2-Amino-3-(2-chlorobenzoyl)-5-(2-carbomethoxyethyl)thiophene is an organic compound characterized by its unique molecular structure, featuring a thiophene ring with various functional groups attached. It is a yellow solid in its pure form, which makes it distinguishable from other compounds.
Uses
Used in Pharmaceutical Industry:
2-Amino-3-(2-chlorobenzoyl)-5-(2-carbomethoxyethyl)thiophene is used as an intermediate in the preparation of platelet-activating factor (PAF) antagonists. PAF antagonists are important in the development of medications targeting a variety of conditions, including cardiovascular diseases and inflammatory disorders. 2-Amino-3-(2-chlorobenzoyl)-5-(2-carbomethoxyethyl)thiophene's role as an intermediate is crucial for synthesizing these therapeutic agents, contributing to the advancement of medical treatments.
As a chemical intermediate, 2-Amino-3-(2-chlorobenzoyl)-5-(2-carbomethoxyethyl)thiophene plays a significant role in the synthesis of various pharmaceutical compounds, particularly those targeting PAF receptors. Its unique structure and properties make it a valuable component in the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 100827-77-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,2 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100827-77:
(8*1)+(7*0)+(6*0)+(5*8)+(4*2)+(3*7)+(2*7)+(1*7)=98
98 % 10 = 8
So 100827-77-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H14ClNO3S/c1-20-13(18)7-6-9-8-11(15(17)21-9)14(19)10-4-2-3-5-12(10)16/h2-5,8H,6-7,17H2,1H3
100827-77-8Relevant articles and documents
Thieno-1,4-diazepines
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, (2008/06/13)
The invention relates to new thieno-1,4-diazepines of general formula STR1 wherein R1, R2, R3, R°, R', Z, X, Y and n have the meanings given in the specification. The new compounds are intended to be used in the treatment of pathological conditions and diseases in which PAF (platelet activating factor) is implicated.
Thieno-traizolo-1,4-diazepino-2-carboxylic acid amides
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, (2008/06/13)
The invention relates to new thieno-traizolo-1,4-diazepino-2-carboxylic acid amides of formula I STR1 wherein R 1 represents hydrogen, a C 1 -C 4 straight-chained or branched alkyl which can optionally be substituted by halogen, preferably Cl or Br, or by hydroxy, cyclopropyl, C 1 -C 3 alkoxy, preferably methoxy, or halogen, preferably chlorine or bromine;R 2 and R 3, each independently, represent hydrogen, a C 1 -C 4 straight-chained or branched alkyl, C 1 -C 4 hydroxyalkyl or the two groups R 2 and R 3 together with the nitrogen atom represent a 5-, 6- or 7-membered ring which optionally contains a nitrogen, oxygen or sulfur atom as a further heteroatom, the second nitrogen atom optionally being substituted by a C 1 -C 4 alkyl, preferably a methyl group;R 4 represents alpha-pyridyl or a phenyl in which the phenyl ring can be substituted preferably in the 2-position, by methyl, halogen, preferably chlorine or bromine, nitro or trifluoromethyl;n represents one of the numbers 0, 1, 2, 3, 4, 5, 6, 7 or 8; and novel intermediates therefor.The compounds of formula I are useful in the treatment of pathological conditions and diseases in which platelet activating factor is implicated.
