100869-87-2Relevant articles and documents
Augmentation of steroidal β-formylenamide with pyrazolo and benzimidazo moieties: A tandem approach to highly fluorescent steroidal heterocycles
Nongthombam, Geetmani Singh,Boruah, Romesh Chandra
, (2021)
A facile synthesis of pyrazolo[1,5-a]pyrimidine and benzimidazo[1,2-a]pyrimidine annulated steroids is described from the novel reaction of β-formyl enamides with amino pyrazoles, indazoles and benzimidazoles. Several of the products exhibited fluorescence properties with high quantum yields.
Iron Catalysis for Modular Pyrimidine Synthesis through β-Ammoniation/Cyclization of Saturated Carbonyl Compounds with Amidines
Chu, Xue-Qiang,Cao, Wen-Bin,Xu, Xiao-Ping,Ji, Shun-Jun
, p. 1145 - 1154 (2018/06/18)
An efficient method for the modular synthesis of various pyrimidine derivatives by means of the reactions of ketones, aldehydes, or esters with amidines in the presence of an in situ prepared recyclable iron(II)-complex was developed. This operationally simple reaction proceeded with broad functional group tolerance in a regioselective manner via a remarkable unactivated β-C-H bond functionalization. Control experiments were performed to gain deep understanding of the mechanism, and the reactions are likely to proceed through a designed TEMPO complexation/enamine addition/transient α-occupation/β-TEMPO elimination/cyclization sequence.
Microwave-assisted Pd-catalyzed synthesis of fused steroidal and non-steroidal pyrimidines from β-halo-α,β-unsaturated aldehydes
Gogoi, Junali,Gogoi, Pranjal,Bezbaruah, Pranjal,Boruah, Romesh C.
, p. 7136 - 7139 (2013/12/04)
A Pd-catalyzed protocol has been developed for the synthesis of fused steroidal and non-steroidal pyrimidines from β-halo-α,β- unsaturated aldehydes under microwave irradiation. The β-halo-α, β-unsaturated aldehydes are synthesized from corresponding keto
