100936-08-1Relevant articles and documents
6-ALKYL- AND 5,6-DIALKYL-2-METHOXY-4(3H)-PYRIMIDINONES IN THE TRANSFORMATIONS OF PYRIMIDINES. REGIOSPECIFIC 1-N-ACYLATION OF PYRIMIDINES.
Botta, Maurizio,Angelis, Francesco De,Finizia, Gabriella,Nicoletti, Rosario
, p. 3345 - 3348 (2007/10/02)
Transformation of 6- and 5,6-dialkyl-2-methoxy-4(3H)-pyrimidinones (1a and 1b) into 1-N-acylated-pyrimidine derivatives 3(a-f) under Friedel-Craft like conditions is presented.In different acylation conditions 4-O-acylated-pyrimidines (5a and 5b) are also obtained.Compounds (3c) and (3f) can be direcly converted into 1-N-acyl-protected-isouridine analogues (8a and 8b).