1009633-72-0

Basic information

• Product Name: C₁₆H₂₂N₄O₈S
• CAS NO: 1009633-72-0
• Molecular Weight: 430.439
• Mol File: 1009633-72-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₂N₄O₈S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₂N₄O₈S(1009633-72-0)
• EPA Substance Registry System: C₁₆H₂₂N₄O₈S(1009633-72-0)

Safety Data

• Hazardous Substances Data: 1009633-72-0(Hazardous Substances Data)

Upstream product

• 188111-79-7 tert-butyl (3R)3-aminopiperidine-1-carboxylate 
• 1656-44-6 2,4-dinitrobenzenesulfonyl chloride 

Downstream Products

• 1009633-76-4 C₂₀H₃₀N₄O₈S 

Relevant articles and documents

Discovery of a series of aminopiperidines as novel iNOS inhibitors

Nitric oxide (NO), a mediator of various physiological and pathophysiological processes, is synthesized by three isozymes of nitric oxide synthase (NOS). Potential candidate clinical drugs should be devoid of inhibitory activity against endothelial NOS (eNOS), since eNOS plays an important role in maintaining normal blood pressure and flow. A new series of aminopiperidines as potent inhibitors of iNOS were identified from a HTS lead. From this study, we identified compound 33 as a potent iNOS inhibitor, with >25-fold selectivity over eNOS and 16-fold selectivity over nNOS.