101080-15-3

Basic information

• Product Name: 2-Thiazolamine, 5-(1-methylethyl)-
• Synonyms: 2-Thiazolamine, 5-(1-methylethyl)-;2-Amino-5-isopropy-thiazole;2-Amino-5-isopropylthiazole;5-isopropyl-1,3-thiazol-2-amine;5-Isopropylthiazol-2-aMine;5-Isopropyl-thiazol-2-ylaMine
• CAS NO: 101080-15-3
• Molecular Formula: C₆H₁₀N₂S
• Molecular Weight: 142.22
• Mol File: 101080-15-3.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 239.364 °C at 760 mmHg
• Flash Point: 98.564 °C
• Appearance: /
• Density: 1.142 g/cm³
• Vapor Pressure: 0.04mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: 2-8°C(protect from light)
• PKA: 5.32±0.10(Predicted)
• CAS DataBase Reference: 2-Thiazolamine, 5-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolamine, 5-(1-methylethyl)-(101080-15-3)
• EPA Substance Registry System: 2-Thiazolamine, 5-(1-methylethyl)-(101080-15-3)

Safety Data

• Hazardous Substances Data: 101080-15-3(Hazardous Substances Data)

Usage

General Description

2-Thiazolamine, 5-(1-methylethyl)- is a chemical compound featuring a thiazole ring with a substituted amine group and an isopropyl group. It is identified by the Chemical Abstracts Service (CAS) number 26538-44-3 and has a molecular formula of C6H10N2S. 2-Thiazolamine, 5-(1-methylethyl)- is used in various chemical and pharmaceutical applications, and its properties and potential uses are still being explored. While there is limited information available on its specific uses and applications, research is ongoing to further understand its potential benefits and uses in various industries.

InChI:InChI=1/C6H10N2S/c1-4(2)5-3-8-6(7)9-5/h3-4H,1-2H3,(H2,7,8)

Upstream product

• 123-51-3 i-Amyl alcohol 
• 590-86-3 isovaleraldehyde 
• 1119-16-0 isocaproic aldehyde 
• 17356-08-0 thiourea 
• 7664-41-7 ammonia 
• 64932-36-1 2-bromo-3-methyl-butyraldehyde 

Downstream Products

• 267654-00-2 BML-259 
• 791122-38-8 (5-isopropyl-thiazol-2-yl)-carbamic acid phenyl ester 
• 267431-23-2 4-nitrophenyl-5-isopropyl-1,3-thiazol-2-ylcarbamate 
• 798572-84-6 N-(4-isopropyl-1,3-thiazol-2-yl)-2-[4-(2-oxo-1,3-oxazolidin-3-yl)phenyl]propanamide 
• 267654-30-8 N-(5-isopropyl-1,3-thiazol-2-yl)-2-(2-bromophenyl)acetamide 
• 1258211-93-6 C₂₂H₂₉FN₈S 
• 1258211-92-5 C₂₂H₂₉FN₈S 
• 1258211-91-4 C₂₂H₂₉FN₈S 
• 1309612-53-0 (2-hydroxybenzoyl)-N-(5-isopropylthiazol-2-yl)amine 
• 1309612-60-9 C₁₅H₁₆N₂O₃S 
• 94680-54-3 5-isopropyl-3-(toluene-4-sulfonyl)-2-(toluene-4-sulfonylimino)-2,3-dihydro-thiazole 
• 492445-66-6 (2S)-2-(4-aminophenyl)-N-(5-isopropyl-1,3-thiazol-2-yl)Propan amide 

Relevant articles and documents

Discovery of imidazo[2,1- b ]thiazole HCV NS4B inhibitors exhibiting synergistic effect with other direct-acting antiviral agents

The design, synthesis, and SAR studies of novel inhibitors of HCV NS4B based on the imidazo[2,1-b]thiazole scaffold were described. Optimization of potency with respect to genotype 1b resulted in the discovery of two potent leads 26f (EC50 = 16

ACTIVATORS OF HIV LATENCY

The present invention relates to novel compounds which active HIV expression in latently infected cells. More particularly, the invention relates to pharmaceutical compositions comprising the novel compounds and their use in activating HIV expression in latently infected cells. Further still, the invention relates to pharmaceutical compositions comprising the novel compounds in combination with anti-HIV therapy compounds and their use in treating HIV infection in both animals and humans. The invention further provides means for preparing the compounds.

Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication

We report the syntheses and activities of a wide range of thiazolides [viz., 2-hydroxyaroyl-N-(thiazol-2-yl)amides] against hepatitis B virus replication, with QSAR analysis of our results. The prototypical thiazolide, nitazoxanide [2-hydroxybenzoyl-N-(5-