101130-77-2

Basic information

• Product Name: 1-(2-(chloromethyl)phenyl)-1H-pyrrole
• Synonyms: 1-(2-(chloromethyl)phenyl)-1H-pyrrole
• CAS NO: 101130-77-2
• Molecular Weight: 191.66
• Mol File: 101130-77-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2-(chloromethyl)phenyl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(chloromethyl)phenyl)-1H-pyrrole(101130-77-2)
• EPA Substance Registry System: 1-(2-(chloromethyl)phenyl)-1H-pyrrole(101130-77-2)

Safety Data

• Hazardous Substances Data: 101130-77-2(Hazardous Substances Data)

Upstream product

• 10333-67-2 methyl 2-(1H-pyrrol-1-yl)benzoate 
• 134-20-3 2-carbomethoxyaniline 
• 446-52-6 2-Fluorobenzaldehyde 
• 394-35-4 methyl 2-fluorobenzoate 
• 61034-86-4 2-(pyrrol-1-yl)-benzyl alcohol 

Downstream Products

• 39243-89-5 2-[2-(pyrrol-1-yl)benzyl]phthalimide 
• 247-66-5 9H-pyrrolo<1,2-a>indole 
• 1092501-71-7 C₁₁H₆⁽²⁾H₃N 
• 317-17-9 pyrrolo[1,2-a]quinoline 
• 117323-80-5 1-Pyridin-2-yl-2-(2-pyrrol-1-yl-benzylsulfanyl)-1,4,5,6-tetrahydro-cyclopentaimidazole 
• 117296-19-2 3-Methoxy-2-[2-(2-pyrrol-1-yl-benzylsulfanyl)-imidazol-1-yl]-pyridine 
• 117296-18-1 3-Methyl-2-[2-(2-pyrrol-1-yl-benzylsulfanyl)-imidazol-1-yl]-pyridine 
• 117296-21-6 2-[2-(2-Pyrrol-1-yl-benzylsulfanyl)-imidazol-1-yl]-pyridine 
• 101130-78-3 1-(2-(chloromethyl)phenyl)-1H-pyrrole-2-carbaldehyde 
• 101130-80-7 1-(2-Chloromethyl-phenyl)-1H-pyrrole-3-carbaldehyde 

Relevant articles and documents

Bronsted Acid Catalyzed Cyclization of Inert N-Substituted Pyrroles to Benzo[ f ]pyrrolo[1,2- a ][1,4]diazepines

Two approaches involving intramolecular and intermolecular cyclization, respectively, have been developed for the direct and practical construction of a series of important benzo[ f ]pyrrolo[1,2- a ][1,4]azepines by using Bronsted acid catalysts. Upon catalysis by TsOH, the intramolecular dehydroxylation/ring closure of 3-hydroxy-2-[2-(1 H -pyrrol-1-yl)benzyl]isoindolin-1-ones provided various racemic benzo[ f ]pyrrolo[1,2- a ][1,4]azepines in high yields. Furthermore, enantioenriched benzo[ f ]pyrrolo[1,2- a ][1,4]azepines were also obtained by chiral phosphoric acid catalyzed intermolecular addition of [2-(1 H -pyrrol-1-yl)phenyl]methanamines to 2-formylbenzoates under mild conditions.

Synthesis of condensed pyrroloindoles via Pd-catalyzed intramolecular C-H bond functionalization of pyrroles

A new strategy for the synthesis of condensed hetero- or carbocycles such as pyrroloindoles or fluorenes has been developed that involves the Pd-catalyzed cyclization of readily available N-(2-halobenzyl)pyrroles or their phenyl derivatives. The reaction is proposed to proceed via oxidative addition of benzylic halides to Pd(0) followed by base-assisted C-H bond activation. A broad range of condensed cyclic products could be obtained in good to excellent yields under mild conditions. Copyright