101169-52-2

Basic information

• Product Name: toluene-4-sulfonic acid 2-oxo-3-phenyl-propyl ester
• Synonyms: toluene-4-sulfonic acid 2-oxo-3-phenyl-propyl ester
• CAS NO: 101169-52-2
• Molecular Weight: 304.367
• Mol File: 101169-52-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: toluene-4-sulfonic acid 2-oxo-3-phenyl-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: toluene-4-sulfonic acid 2-oxo-3-phenyl-propyl ester(101169-52-2)
• EPA Substance Registry System: toluene-4-sulfonic acid 2-oxo-3-phenyl-propyl ester(101169-52-2)

Safety Data

• Hazardous Substances Data: 101169-52-2(Hazardous Substances Data)

Upstream product

• 114395-16-3 (±)-trans-(3-phenyloxiran-2-yl)methyl 4-methylbenzenesulfonate 
• 104-15-4 toluene-4-sulfonic acid 
• 103-79-7 1-phenyl-acetone 
• 186581-53-3 diazomethane 
• 103-80-0 phenylacetyl chloride 

Relevant articles and documents

β-fluoroamphetamines via the stereoselective synthesis of benzylic fluorides

A range of substituted aryl epoxides undergo efficient ring-opening hydrofluorination upon treatment with 0.33 equiv of BF3-OEt 2 in CH2Cl2 at -20 -°C to give the corresponding syn-fluorohydrins, consistent with a mechanism involving a stereoselective SN1-type epoxide ring-opening process. The benzylic fluoride products of these reactions are valuable templates for further elaboration, as demonstrated by the preparation of a range of aryl-substituted β-fluoroamphetamines.