1012785-60-2

Basic information

• Product Name: 2,2-bis(benzyloxymethyl)-3-bromo-1-tert-butyldimethylsilyloxymethyl-3-fluorocyclopropane
• Synonyms: 2,2-bis(benzyloxymethyl)-3-bromo-1-tert-butyldimethylsilyloxymethyl-3-fluorocyclopropane
• CAS NO: 1012785-60-2
• Molecular Weight: 523.558
• Mol File: 1012785-60-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-bis(benzyloxymethyl)-3-bromo-1-tert-butyldimethylsilyloxymethyl-3-fluorocyclopropane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-bis(benzyloxymethyl)-3-bromo-1-tert-butyldimethylsilyloxymethyl-3-fluorocyclopropane(1012785-60-2)
• EPA Substance Registry System: 2,2-bis(benzyloxymethyl)-3-bromo-1-tert-butyldimethylsilyloxymethyl-3-fluorocyclopropane(1012785-60-2)

Safety Data

• Hazardous Substances Data: 1012785-60-2(Hazardous Substances Data)

Upstream product

• 1868-53-7 dibromofluoromethane 
• 552879-97-7 tert-Butyldimethylsilyl-3-benzyloxymethyl-4-benzyloxy-2-butenol 

Downstream Products

• 1012785-61-3 (+/-)-tert-Butyldimethylsilyl-[2,2-bis(benzyloxymethyl)-3-fluorocyclopropyl]methanol 
• 604785-90-2 2,2-bis(benzyloxymethyl)-3-fluoro-1-(hydroxymethyl)cyclopropane 
• 1012785-63-5 C₂₆H₂₆NO₅FSe 
• 1012785-62-4 2,2-bis(benzyloxymethyl)-3-fluoro-1-(((2-nitrophenyl)selenyl)methyl)cyclopropane 
• 1012785-70-4 (E)-2-amino-6-chloro-9-{[2,2-bis(benzyloxymethyl)-3-fluorocyclopropylidene]methyl}purine 
• 1012785-71-5 (Z)-2-amino-6-chloro-9-{[2,2-bis(benzyloxymethyl)-3-fluorocyclopropylidene]methyl}purine 
• 1012785-66-8 (E)-9-{[2,2-bis(benzyloxymethyl)-3-fluorocyclopropylidene]methyl}adenine 
• 1012785-67-9 (Z)-9-{[2,2-bis(benzyloxymethyl)-3-fluorocyclopropylidene]methyl}adenine 
• 1012785-65-7 2,2-bis(benzyloxymethyl)-1-bromo-1-bromomethyl-3-fluorocyclopropane 
• 1012785-64-6 2,2-bis(benzyloxymethyl)-3-fluoro-1-methylenecyclopropane 

Relevant articles and documents

Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: Synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3- fluorocyclopropylidene]methyl}-adenines and guanines

Synthesis of fluorinated cyclopropavir analogues 13a, 13b, 14a, and 14b is described starting from alkene 15. Addition of carbene derived from dibromofluoromethane gave bromofluoro cyclopropane 16. Reduction (compound 17) followed by desilylation gave int