101342-39-6

Basic information

• Product Name: 2-amino-4-phenyl-4H-pyran-3,5-dicarbonitrile
• Synonyms: 2-amino-4-phenyl-4H-pyran-3,5-dicarbonitrile
• CAS NO: 101342-39-6
• Molecular Weight: 223.234
• Mol File: 101342-39-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-amino-4-phenyl-4H-pyran-3,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-phenyl-4H-pyran-3,5-dicarbonitrile(101342-39-6)
• EPA Substance Registry System: 2-amino-4-phenyl-4H-pyran-3,5-dicarbonitrile(101342-39-6)

Safety Data

• Hazardous Substances Data: 101342-39-6(Hazardous Substances Data)

Upstream product

• 19362-96-0 2-(1-hydroxybenzyl)acrylonitrile 
• 100-52-7 benzaldehyde 
• 2700-22-3 Benzylidenemalononitrile 
• 58243-06-4 trans-1-diethylamino-2-cyanoethene 
• 56069-64-8 2-Cyano-3-phenylpropenal 
• 109-77-3 malononitrile 

Downstream Products

• 1070-71-9 propiolonitrile 
• 709-79-5 (E)-2-cyano-3-phenylacrylamide 
• 117226-94-5 3,5-dicyano-3,4-dihydro-4-phenyl-2(1H)-pyridinone 
• 117226-97-8 3,5-dicyano-4-phenyl-2(1H)-pyridinone 

Relevant articles and documents

Design, synthesis, and biological evaluation of 4-H pyran derivatives as antimicrobial and anticancer agents

A series of pyran derivatives (5–27) were synthesized in good yields by utilizing Baylis–Hillman chemistry and were further investigated for their in vitro anticancer, antibacterial, and antifungal activities. Most of the tested compounds exhibited promis

Ring Transformation of Isoxazoles into Furan and Pyran Derivatives

A ring transformation of isoxazole into 3,5-dicyano-4H-pyran-2-amines (4) and N-arylidenefuran-2-amines (7) is reported.It involves a ring opening of the isoxazole ring in the presence of an aromatic aldehyde, leading to 2-arylidene-3-oxopropanenitrile (2), followed by nucleophilic attack by either cyanide or propanedinitrile and then heterocyclization.The reaction can also be applied to 5-substituted isoxazoles.