10139-02-3 Usage
Description
P-NITROPHENYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE is a chemical compound that serves as a substrate for various enzymatic assays. It is an N-acetyl-alpha-D-glucosaminide in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group. This white solid is widely utilized in the detection and study of certain genetic disorders and enzymatic activities.
Uses
1. Used in Medical Diagnostics:
P-NITROPHENYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE is used as a diagnostic substrate for the detection of Sanfilippo syndrome B, also known as mucopolysaccharidosis type IIIB. This is a rare genetic disorder characterized by the deficiency of the enzyme N-acetyl-alpha-galactosaminidase, which is essential for the breakdown of complex sugar molecules. The compound aids in identifying the presence of this enzyme deficiency, thus helping in the early diagnosis and management of the condition.
2. Used in Enzyme Assays:
P-NITROPHENYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE is used as a substrate for assays of N-acetyl-alpha-galactosaminidase and b-L-fucosidases. These assays are crucial for studying the activity and function of these enzymes, which play a significant role in various biological processes. By using this compound as a substrate, researchers can gain insights into the enzymatic mechanisms and their potential applications in therapeutic interventions.
3. Used in Research and Development:
In the field of research and development, P-NITROPHENYL 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSIDE serves as an essential tool for understanding the structure and function of various enzymes, particularly those involved in the metabolism of complex carbohydrates. This knowledge can be applied to develop novel therapeutic strategies for treating diseases associated with enzyme deficiencies or abnormalities in carbohydrate metabolism.
Biochem/physiol Actions
4-Nitrophenyl N-acetyl-α-D-glucosaminide is used as a substrate for analysing β-hexoaminidase activity at 37°C and analysed at 405 nm.
Check Digit Verification of cas no
The CAS Registry Mumber 10139-02-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,3 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 10139-02:
(7*1)+(6*0)+(5*1)+(4*3)+(3*9)+(2*0)+(1*2)=53
53 % 10 = 3
So 10139-02-3 is a valid CAS Registry Number.
